Results 61 to 70 of about 7,611 (233)

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Eosinophilic airway inflammation and eosinophilic chronic rhinosinusitis during nivolumab and ipilimumab [PDF]

Respirology Case Reports, 2020
AbstractImmune‐related adverse events (irAEs) are induced by immune checkpoint inhibitors (ICIs) which are administered for many cancers. There are many irAEs such as endocrine abnormalities, interstitial lung disease, and colitis. However, irAEs associated with type 2 (T2) inflammation are less known. We herein report a 71‐year‐old woman who developed
Hirofumi Watanabe, Kazuhiro Asada, Toshihiro Shirai, Hiroko Torii, Koji Yoshimura, Kimihide Kusafuka   +5 more
openaire   +3 more sources

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

CCAD or eCRS: Defining Eosinophilic Subpopulations in Chronic Rhinosinusitis

, 2023
Background: Central compartment atopic disease (CCAD) and eosinophilic chronic rhinosinusitis (eCRS) are two clinical phenotypes of primary diffuse type 2 chronic rhinosinusitis (CRS) defined in the European Position Paper on Rhinosinusitis 2020 ...
Sit, A, Rimmer, J, Kalish, L, Earls, P, Sewell, W ; https://orcid.org/, Alvarado, R ; https://orcid.org/, Harvey, RJ ; https://orcid.org/, Campbell, R   +7 more
core   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Assessing Surgical Extent in Endoscopic Sinus Surgery: A Scoping Review of Scoring Systems

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Endoscopic sinus surgery (ESS) varies substantially in the extent of surgical dissection performed, even when described under the same procedural label. In chronic rhinosinusitis, this heterogeneity may influence postoperative outcomes, revision rates, and response to biologic therapies.
Alexander Lein, Marie T. Ehrgott, Linda Liu, Archana Jaiswal, Rajiv K. Bhalla, Noel Ayoub, Faris F. Brkic, David T. Liu   +7 more
wiley   +1 more source

Periostin is an aggravating factor and predictive biomarker of eosinophilic chronic rhinosinusitis

, 2023
Background: Patients with eosinophilic chronic rhinosinusitis (ECRS) respond poorly to many treatment modalities. Overproduction of periostin in the nasal mucosa is reported to contribute to polyp formation.
Nobuo Ohta, Keigo Murakami, Kazuhiro Murakami, Teruyuki Sato, Hiroki Ikeda, Shion Shirane   +5 more
core   +1 more source

Sinus Microbiota in Patients With Eosinophilic and Non-Eosinophilic Chronic Rhinosinusitis With Nasal Polyps [PDF]

, 2021
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by Th2-skewed inflammation and increased colonization by Staphylococcus aureus. CRSwNP can be distinguished as eosinophilic (ECRSwNP) and non-eosinophilic (NECRSwNP) by the infiltration ...
Ying Li, Li, Min, Jianchen Fang, Jiping Li, Feng, Tingting, Jiali Shi, Liu, Bin, Nana Ren, Min Li, Ren, Nana, Bin Liu, Bao, Ximing, Xu, Ji, Tingting Feng, Yao Liu, Cao, Wanxin, Qian Liu, Ping Miao, Wanxin Cao, Liu, Yao, Li, Ying, Liu, Qian, Ximing Bao, Fang, Jianchen, Miao, Ping, Ji Xu, Shi, Jiali, Li, Jiping   +27 more
core   +1 more source

Allergic Aspergillus Rhinosinusitis

Journal of Fungi, 2016
Allergic fungal rhinosinusitis (AFRS) is a unique variety of chronic polypoid rhinosinusitis usually in atopic individuals, characterized by presence of eosinophilic mucin and fungal hyphae in paranasal sinuses without invasion into surrounding mucosa ...
Arunaloke Chakrabarti, Harsimran Kaur
doaj   +1 more source

Eosinophilic asthma with chronic rhinosinusitis/nasal polyps and biologic agents

, 2019
The current understanding in severe asthma management is the targeted therapy approach with the evaluation of phenotypes and biomarkers. Therefore, personalized treatments are recently more prominent. Eosinophilic asthma with chronic rhinosinusitis/nasal
YILMAZ, İNSU
core   +1 more source