Results 51 to 60 of about 1,778,131 (183)

Assessing the Mucosal Inflammatory Endotype of Obesity in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory syndrome of the paranasal sinuses that is defined phenotypically as either with nasal polyps (CRSwNP) or without nasal polyps (CRSsNP). More recently, inflammatory markers have been used to cluster patients into putative endotypes that are presumed to have a common ...
Jeffanie W. Gayoso, Li‐Ching Huang, Quanhu Sheng, Daniel Lofgren, Ping Li, Katherine Cahill, Mason Krysinski, Rakesh K. Chandra, Justin H. Turner, Naweed Chowdhury   +9 more
wiley   +1 more source

The Mixed Neutrophilic–Eosinophilic Endotype of CRSwNP Blunts Postsurgical Improvement as Determined by the Completeness of Surgery Index

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The Completeness of Surgery Index (CoSI) is a novel metric for assessing surgical quality in chronic rhinosinusitis with nasal polyps (CRSwNP). Structured histopathology (SHP) is helpful for characterizing drivers of inflammation. Integrating these two tools to identify patients at higher risk for surgically recalcitrant disease has
Vidit M. Talati, Kerol Faltas, Michael R. Xiang, Randy Bach, Spencer L. Yueh, Margaret B. Mitchell, Alan D. Workman, Michael A. Kohanski, Nithin D. Adappa, Jennifer E. Douglas, Noam A. Cohen, John V. Bosso, James N. Palmer   +12 more
wiley   +1 more source

Biomarkers and Biologics in Chronic Rhinosinusitis [PDF]

, 2022
Eosinophilic chronic rhinosinusitis (eCRS) or type 2 dominant chronic rhinosinusitis (CRS) is a complex inflammatory disease mediated by type-2 cytokines, including interleukin (IL)-5. Management of this condition is often difficult, requiring multimodal
Ho, Jacqueline
core   +1 more source

Allergic Aspergillus Rhinosinusitis

Journal of Fungi, 2016
Allergic fungal rhinosinusitis (AFRS) is a unique variety of chronic polypoid rhinosinusitis usually in atopic individuals, characterized by presence of eosinophilic mucin and fungal hyphae in paranasal sinuses without invasion into surrounding mucosa ...
Arunaloke Chakrabarti, Harsimran Kaur
doaj   +1 more source

Kesesuaian Endotipe dengan Skor Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) pada Rinosinusitis Kronik

, 2022
Latar Belakang: Rinosinusitis kronik (RSK) merupakan salah satu penyakit di bidang THT-KL yang masih menjadi beban kesehatan di suatu negara. Selain menurunkan kualitas hidup penderitanya, strategi penatalaksanaan RSK masih merupakan tantangan di ...
Dr. dr. H. Edi Handoko,, Sp. T.H.T.B.K.L. Subsp.Oto.(K),, dr. Iriana Maharani,, Sp. T.H.T.B.K.L. Subsp.Rino.(K), FICS, Christianty, dr. Finna   +2 more
core  

Comparison of olfactory and taste functions between eosinophilic and non-eosinophilic chronic rhinosinusitis

, 2020
Objective: Most patients with chronic rhinosinusitis (CRS) complain of olfactory and/or taste dysfunctions. However, olfactory and taste dysfunctions depending on the subtype of CRS, classified as eosinophilic CRS (ECRS) and non-eosinophilic CRS (NCRS ...
윤주헌, 하종균, 김창훈, 조형주   +3 more
core   +1 more source

Combination Biologic Therapy with Mepolizumab and Dupilumab for Severe Eosinophilic Granulomatosis with Polyangiitis and Chronic Rhinosinusitis with Nasal Polyp [PDF]

We report the case of a 55-year-old female with eosinophilic granulomatosis with polyangiitis and chronic rhinosinusitis with nasal polyp. Rhinosinusitis recurred 6 months after full-house endoscopic sinus surgery.
竹内,裕美, Takeuchi,Hiromi, Fujiwara,Kazunori, タケウチ,ヒロミ, ナカムラ,ヨウスケ, フジワラ,カズノリ, 中村,陽祐, Nakamura,Yosuke, Kimura,Toru, Kikumoto,Naoki, Nakamori,Motoki, 藤原,和典   +11 more
core   +2 more sources

System‐Local Axes and Metabolic Reprogramming From Health to Response in House Dust Mite‐Specific Subcutaneous Immunotherapy for Allergic Rhinitis

iMetaMed, EarlyView.
This study delineated nasal‐plasma metabolic reprogramming in house dust mite‐allergic rhinitis (HDM‐AR) and subcutaneous immunotherapy (SCIT) response, showing compartment‐specific signatures dominated by nasal lipid‐redox and plasma nucleotide‐NAD+ axes and across the HC–HDM‐AR–SCIT response continuum, dual‑compartment metabolites exhibited ...
Bixing Fang, Fei Pan, Yachun Li, Yimeng Wang, Ze Wang, Zhiheng Huang, Ming Chen, Yun Li, Mengli Huang, Cheng Guo, Chubo Xie, Lina Dong, Yadong Gao, Zhuohang Yu   +13 more
wiley   +1 more source

The Role of Artificial Intelligence in Modern Allergology: A Review of Applications in Diagnosis, Prediction, and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig, Stephan Traidl, Sonja Mathes   +2 more
wiley   +1 more source

Determining the Severity of Symptoms Among Patients with Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis Versus Non - Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis at the Veterans Memorial Medical Center

Philippine Journal of Otolaryngology Head and Neck Surgery
Objective: To compare the severity of symptoms of patients diagnosed with Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis (eCRSwNP) versus Non - Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis (non-eCRSwNP) using the Filipino ...
Geoffrey John Hizon, Jay Espanto, Kathleen Rodriguez-Labrador   +2 more
doaj   +1 more source