Eosinophil Peroxidase as a Dynamic Indicator of Treatment Response in Eosinophilic Chronic Rhinosinusitis. [PDF]
Int Forum Allergy RhinolKey Points Eosinophil peroxidase (EPX) correlates with local type 2 inflammation and may serve as a noninvasive biomarker of eosinophilic chronic rhinosinusitis ...
Callander JK +9 more
europepmc +3 more sources
Alterations of gut microbiome in eosinophilic chronic rhinosinusitis. [PDF]
Eur Arch OtorhinolaryngolA growing body of evidence has elucidated that the gut microbiota has a crucial impact on the pathophysiological process of atopic diseases. Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is a local atopic disease of the systemic immune response.
Liang Y +8 more
europepmc +3 more sources
Reduced nasal nitric oxide levels in patients with eosinophilic chronic rhinosinusitis
Allergology International, 2019 Background: In Eosinophilic chronic rhinosinusitis (ECRS), it is difficult to estimate the refractoriness and recurrence risk for each patient. Fraction of exhaled nitric oxide (FeNO) is known as a biomarker of eosinophilic inflammation in lower airway ...
Kanako Yoshida +5 more
doaj +2 more sources
In office sampling of eosinophil peroxidase to diagnose eosinophilic chronic rhinosinusitis. [PDF]
Int Forum Allergy RhinolAbstractBackgroundPractical biomarkers for endotypic characterization of chronic rhinosinusitis (CRS) remain elusive, hindering clinical utility. Eosinophil peroxidase (EPX) is an enzyme released by activated eosinophils. The objective of this study was to evaluate a clinic EPX assay as a marker of eosinophilic CRS.MethodsSubjects with and without CRS ...
Callander JK +11 more
europepmc +5 more sources
IL-5 and IL-6 are increased in the frontal recess of eosinophilic chronic rhinosinusitis patients
Journal of Otolaryngology - Head and Neck Surgery, 2017 Background Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow-up period.
Kazunori Kubota +5 more
doaj +2 more sources
iScienceSummary: Eosinophilic chronic rhinosinusitis (ECRS) is a distinct subset of chronic rhinosinusitis characterized by heightened eosinophilic infiltration and increased symptom severity, often resisting standard treatments.
Panhui Xiong +9 more
doaj +2 more sources
Assessing chronic rhinosinusitis with nasal polyps severity by “Japanese epidemiological survey of refractory eosinophilic chronic rhinosinusitis” algorithm [PDF]
Exploration of Asthma & Allergy, 2023 Aim: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex disease with different subtypes that affect patients’ quality of life. This study aim to evaluate the severity of CRSwNP and the risk of treatment resistance using the “Japanese ...
Sérgio Duarte Dortas Jr +7 more
doaj +1 more source
The effect of macrolides on allergic rhinitis versus chronic rhinosinusitis- an in-vitro study [PDF]
, 2009 PhDBackground The mechanisms of the rhinitic process are complex. Previous studies upon nasal epithelial cells have begun to investigate rhinitis.
Kuchai, Romana
core +4 more sources
Endotyping of nasal polyps in a multiracial Asian population [PDF]
Rhinology Online, 2022 Background: Chronic rhinosinusitis is a heterogenous disease with variation in the endotypes of nasal polyps, with type 2 inflammation being more prevalent in Caucasian populations whereas Chinese populations are more heterogenous. We aim to describe the
Shuhui Xu +4 more
doaj +1 more source
Interferon-α action in cytokine profile in eosinophilic nasal polyp cultures
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: Chronic rhinosinusitis is currently classified into two types: chronic rhinosinusitis without nasal polyps and chronic rhinosinusitis with nasal polyps.
Júlio Cláudio Sousa +5 more
doaj +1 more source