Results 41 to 50 of about 7,611 (233)

Eosinophilic Chronic Rhinosinusitis

Practica Oto-Rhino-Laryngologica, 2013
비부비동염은 비폐색, 점액성 비루, 두통, 후각장애 등의 증 상을 동반하는 비부비동 점막의 염증성 질환이다. 급성비부 비동염의 경우 바이러스와 세균 감염이 주된 병인으로 알려져 있지만 만성비부비동염의 경우 그 원인과 병태생리에 대한 다 양한 주장과 가설이 제시되고 있다. 만성비부비동염의 분류 또한 증상의 정도, 동반질환의 종류, 약물 혹은 수술적 치료 방법 등에 따라 다양하게 나누어지고 있다. 일반적으로 비용 의 동반유무와 조직내 호산구 증가유무에 따른 분류는 치료 방법의 선택과 예후 판단에 도움이 된다.
Fujieda, Shigeharu, Sakashita, Masafumi, Imoto, Yoshimasa   +2 more
openaire   +2 more sources

Pathogenesis of chronic rhinosinusitis with nasal polyp and a prominent T2 endotype

Heliyon, 2023
Chronic rhinosinusitis is a heterogenous and multifactorial disease, characterized by persistent inflammation of the nose and paranasal sinuses, which causes nasal obstruction, nasal discharge, facial pain, and smell disturbance.
Said Ahmad Shah, Masayoshi Kobayashi
doaj   +1 more source

Olfactory Bulb Volume and Function Recovery in Eosinophilic Chronic Rhinosinusitis. [PDF]

Laryngoscope
This study investigated perioperative changes in olfactory bulb volume (OBV) in patients with eosinophilic chronic rhinosinusitis using high‐resolution 3T MRI. Postoperative increases in OBV were associated with improvements in olfactory identification, suggesting a potential link between olfactory bulb structural plasticity and functional recovery ...
Yamamoto K, Abukawa M, Okuni T, Nakanishi M, Sakurai Y, Yama N, Ogasawara N, Kamekura R, Takano K.   +8 more
europepmc   +2 more sources

Epigenetics of chronic rhinosinusitis and the role of the eosinophil [PDF]

International Forum of Allergy & Rhinology, 2011
AbstractBackground:One theory for the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) involves aberration in the expression of genes that maintain the sinonasal innate immune system. We propose that the alteration in gene expression seen in CRSwNP is a result of oxidative byproducts of eosinophils.
Kristin A, Seiberling, Christopher A, Church, Jason L, Herring, Lawrence C, Sowers   +3 more
openaire   +2 more sources

The changes of clinical and histological characteristics of chronic rhinosinusitis in 18 years: Was there an inflammatory pattern shift in southern China?

World Allergy Organization Journal, 2021
Background: Nowadays, the heterogeneity of chronic rhinosinusitis (CRS) has attracted extensive attention. The histological patterns and clinical characteristics may vary greatly in different areas and among different groups of people.
Xin Luo, Zhaofeng Xu, Kejun Zuo, Jie Deng, Wenxiang Gao, Lijie Jiang, Lei Xu, Zhaoqi Huang, Jianbo Shi, Yinyan Lai   +9 more
doaj   +1 more source

The SWI/SNF complex in eosinophilic and non eosinophilic chronic rhinosinusitis

Acta Otorhinolaryngologica Italica, 2021
Chronic rhinosinusitis (CRS) can be classified as eosinophilic (eCRS) or non-eosinophilic (neCRS) based on infiltration type. The SWI/SNF complex may be involved in the pathophysiology of CRS.To assess the expression of the SWI/SNF complex in both CRS groups; to correlate blood eosinophil count (BEC), and histopathology eosinophil count (HPEC) with the
Katarzyna Kowalik, Martyna Waniewska-Leczycka, Elzbieta Sarnowska, Natalia Rusetska, Marcin Ligaj, Alicja Chrzan, Mariola Popko   +6 more
openaire   +4 more sources

Predictors of the enhanced response to mepolizumab treatment for severe eosinophilic asthma: A retrospective, long-term study

Cogent Medicine, 2020
Mepolizumab significantly reduces the number of annual exacerbations (AEs) and the maintenance dose of systemic corticosteroids (CSs) in patients with severe eosinophilic asthma (SEA).
Takanori Numata, Hanae Miyagawa, Hironori Kawamoto, Masahiro Yoshida, Hirofumi Utsumi, Mitsuo Hashimoto, Shunsuke Minagawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano   +9 more
doaj   +1 more source

Gαi1/3 signaling mediates IL-5-induced eosinophil activation and type 2 inflammation in eosinophilic chronic rhinosinusitis [PDF]

Frontiers in Immunology
Huanxia Xie, Jiang Ji, Zhichen Liu
exaly   +2 more sources

The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma

Allergy, Asthma & Clinical Immunology, 2011
This case reports the unique association of eosinophilic gastrointestinal disease with eosinophilic bronchitis, asthma and chronic rhinosinusitis and some features of lymphocytic hypereosinophilic syndrome, describes a diagnostic protocol for patients ...
Nair Parameswaran, Ochkur Sergei I, Protheroe Cheryl, Simms Elizabeth, Lee Nancy A, Lee James J   +5 more
doaj   +1 more source

Treatments of refractory eosinophilic lung diseases with biologics

Allergology International, 2023
Biologics targeting the molecules associated with type 2 inflammation have significantly improved the outcomes of patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps (CRSwNP).
Koichiro Asano, Yuzo Suzuki, Jun Tanaka, Konomi Kobayashi, Yosuke Kamide   +4 more
doaj   +1 more source