Results 51 to 60 of about 105,068 (238)

Proton Pump Inhibitor Therapy for Eosinophilic Esophagitis: History, Mechanisms, Efficacy, and Future Directions

Journal of Asthma and Allergy, 2022
Over the past decade, the role of proton pump inhibitor (PPI) medication has evolved from a diagnostic tool for Eosinophilic Esophagitis (EoE), by excluding patients with PPI responsive esophageal eosinophilia (PPI-REE), to a therapy for EoE.
J. Franciosi, E. Mougey, E. Dellon, C. Gutiérrez‐Junquera, S. Fernández-Fernández, R. Venkatesh, S. Gupta   +6 more
semanticscholar   +1 more source

Eosinophilic esophagitis with extremely high esophageal eosinophil counts [PDF]

Journal of Allergy and Clinical Immunology, 2021
Patients with eosinophilic esophagitis (EoE) and extremely high esophageal eosinophilia have a distinct endotype defined by more severe atopic, endoscopic, histologic, and transcriptomic features.
Kelly M, O'Shea, Mark, Rochman, Tetsuo, Shoda, Nives, Zimmermann, Julie, Caldwell, Marc E, Rothenberg   +5 more
openaire   +2 more sources

Eosinophilic esophagitis presenting with spontaneous esophageal rupture: a case report

Journal of Medical Case Reports, 2019
Background Eosinophilic esophagitis, once considered a rare disorder, has been increasingly recognized as a leading cause of dysphagia and food impaction in children and adults over the last few decades.
Tanureet Kochar, Parminder Singh Dhingra, Muhammad Farhan Khaliq, Brittain Mcjunkin   +3 more
doaj   +1 more source

Clonally expanded, GPR15-expressing pathogenic effector TH2 cells are associated with eosinophilic esophagitis

Science immunology, 2021
TH2 cells in eosinophilic esophagitis exhibit clonotypic features of an antigen-specific response and enhanced esophagus-homing ability. Pathogenic esophageal TH2 cells Eosinophilic esophagitis (EoE) is an allergic disease triggered by exposure to food ...
D. Morgan, B. Ruiter, Neal P. Smith, Ang A. Tu, Brinda Monian, Brandon E. Stone, Navneet K. Virk-Hundal, Qian Yuan, W. Shreffler, J. C. Love   +9 more
semanticscholar   +1 more source

Eosinophilic Esophagitis as One of the Manifestations of Gastrointestinal Food Allergy in Children

Zdorovʹe Rebenka, 2015
The article describes the features of clinical course and current approaches to the diagnosis and treatment of eosinophilic esophagitis in school-aged children.
S.L. Niankovskyi, M.I. Horodylovska, V.A. Ivantsiv, O.I. Boiko   +3 more
doaj   +1 more source

Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis.

New England Journal of Medicine
BACKGROUND Benralizumab is an eosinophil-depleting anti-interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.
M. Rothenberg, Evan S. Dellon, M. Collins, A. Bredenoord, I. Hirano, Kathryn A Peterson, L. Brooks, J. Caldwell, Harald Fjällbrant, H. Grindebacke, C. Ho, Matthew Keith, C. Mccrae, D. Sinibaldi, Wendy White, Catherine J Datto   +15 more
semanticscholar   +1 more source

Eosinophilic esophagitis: Immune mechanisms and therapeutic targets

Clinical and Experimental Allergy, 2022
Eosinophilic esophagitis (EoE) is an emerging chronic inflammatory disease of the oesophagus and is clinically characterized by upper gastrointestinal (GI) symptoms including dysphagia and esophageal food impaction.
Dilawar Khokhar, Sahiti Marella, Gila Idelman, Joy W. Chang, M. Chehade, Simon Hogan   +5 more
semanticscholar   +1 more source

Eosinophilic esophagitis [PDF]

Orvosi Hetilap, 2010
Az eosinophil oesophagitis (EO) olyan, többnyire orális antigénmediált, idült, reverzíbilis, eosinophil granulocyták okozta nyelőcsőgyulladás, amely dysphagiához, fokozódó nyelőcsőszűkülethez és falatelakadáshoz vezethet. A tünetek gyakran emlékeztetnek a gastrooesophagealis refluxbetegségre (GORB).
Dóra, Lippai, Zsolt, Tulassay
openaire   +2 more sources

Endoscopic findings of gastric lesions in patients with eosinophilic gastrointestinal disorders

Endoscopy International Open, 2020
Background and study aims Eosinophilic gastrointestinal disorders are classified into eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis, and eosinophilic colitis according to the site of eosinophilic infiltration.
Yasuhiro Fujiwara, Kojiro Tanoue, Akira Higashimori, Yu Nishida, Masatsugu Maruyama, Shigehiro Itani, Masaki Ominami, Yuji Nadatani, Shusei Fukunaga, Koji Otani, Shuhei Hosomi, Fumio Tanaka, Noriko Kamata, Yasuaki Nagami, Koichi Taira, Hirohisa Machida, Tetsuya Tanigawa, Toshio Watanabe, Masahiko Ohsawa   +18 more
doaj   +1 more source

Updated international consensus diagnostic criteria for eosinophilic esophagitis: Proceedings of the AGREE conference

Gastroenterology, 2018
Background and Aims: Over the last decade, clinical experiences and research studies raised concerns regarding use of proton pump inhibitors (PPIs) as part of the diagnostic strategy for eosinophilic esophagitis (EoE). We aimed to clarify the use of PPIs
E. Dellon, C. Liacouras, J. Molina-Infante, G. Furuta, J. Spergel, N. Zevit, S. Spechler, S. Attwood, A. Straumann, S. Aceves, J. Alexander, D. Atkins, Nicoleta C. Arva, C. Blanchard, P. Bonis, W. Book, K. Capocelli, M. Chehade, Edaire Cheng, M. Collins, C. Davis, J. Dias, C. Di Lorenzo, R. Dohil, C. Dupont, G. Falk, C. T. Ferreira, A. Fox, N. Gonsalves, S. Gupta, D. Katzka, Y. Kinoshita, C. Menard-Katcher, Ellyn Kodroff, D. Metz, S. Miehlke, A. Muir, V. Mukkada, S. Murch, S. Nurko, Y. Ohtsuka, R. Orel, Alexandra Papadopoulou, K. Peterson, H. Philpott, P. Putnam, J. Richter, R. Rosen, M. Rothenberg, A. Schoepfer, Melissa Scott, N. Shah, J. Sheikh, R. Souza, M. Strobel, N. Talley, M. Vaezi, Y. Vandenplas, M. Vieira, M. Walker, J. Wechsler, B. Wershil, T. Wen, Guang-Yu Yang, I. Hirano, A. Bredenoord   +65 more
semanticscholar   +1 more source