Results 81 to 90 of about 23,885 (300)
Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino +3 more
wiley +1 more source
Investigating Airway Symptoms in Eosinophilic Esophagitis (EoE)
The Laryngoscope, EarlyView.ABSTRACT Objectives Diagnostic delay of eosinophilic esophagitis (EoE) is significant, and efforts are needed to raise awareness and reduce prolonged symptoms and complications. Airway and swallowing symptoms often overlap, especially in children, complicating diagnosis and increasing delays.
Angela Huynh +6 more
wiley +1 more source
Jornal de Pediatria (Versão em Português), 2018 Objectives: To translate and culturally adapt the Pediatric Eosinophilic Esophagitis Symptom Score (version 2.0), a tool used to assess pediatric eosinophilic esophagitis symptoms reported by patients and/or their parents/caregivers.
Maria Fernanda Oliveira Santos +3 more
doaj +3 more sources
Canadian Journal of Gastroenterology, 2012 BACKGROUND: Celiac disease and eosinophilic esophagitis are usually considered to be separate gastrointestinal diseases; however, it appears that they may coexist more often than would be expected.
Joseph R Abraham +3 more
doaj +1 more source
Eosinophilic esophagitis, celiac disease, and immunoglobulin E–mediated allergy in a 2-year-old child [PDF]
, 2011 This communication was presented at XXVI National Congress of SEAIC, Spanish Society of Allergology and Clinical Immunology, Bilbao, Spain, 2008Celiac disease, eosinophilic esophagitis, and urticaria are 3 manifestations of food allergy with different ...
Escudero, C. +6 more
core +1 more source
Erosive Eosinophilic Esophagitis in Rumination Syndrome [PDF]
, 2009 Rumination syndrome involves bringing up partially digested food into the pharynx voluntarily, followed by reswallowing or expelling. It was discovered in the 17th century; however, knowledge of the disorder has remained sparse until recently.
Rick, James R, Sidhu, Shawn S
core +2 more sources
Molecular Nutrition &Food Research, EarlyView.The bacterial enzyme microbial transglutaminase (mTG) is widely used in the food industry as a technological aid to improve textural properties of a multitude of food products. mTG mimics the enzymatic function of human transglutaminase 2 (TG2) and may play a role in the pathogenesis of celiac disease.
Sebastian Stricker +3 more
wiley +1 more source
Eosinophilic esophagitis: manometric and pHmetric findings
Arquivos de Gastroenterologia, 2012 CONTEXT: Eosinophilic esophagitis is an entity characterized by an esophageal inflammatory infiltrate of eosinophils, manifested by dysphagia, intermittent food impactions and symptoms similar to gastroesophageal reflux disease (GERD), that predominantly
Monica Maria Cardoso Monnerat +1 more
doaj +1 more source
State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna +4 more
wiley +1 more source