Results 81 to 90 of about 110,204 (324)

Emerging incidence trends of eosinophilic esophagitis over 25 years: Results of a nationwide register‐based pathology cohort

Neurogastroenterology and Motility, 2021
Eosinophilic esophagitis (EoE) has emerged from a case‐reportable illness in the early 1990s to a distinct clinicopathological entity. Increasing worldwide incidences have been observed, although due to various study designs estimates are inconsistent.
W. D. de Rooij, Marielle E Barendsen, M. Warners, B. V. van Rhijn, J. Verheij, A. Bruggink, A. Bredenoord   +6 more
semanticscholar   +1 more source

Eosinophilic Esophagitis and Allergy [PDF]

Digestive Diseases, 2014
Eosinophilic esophagitis (EoE) has been associated with allergic diseases of the airways and skin. Here, we review the current literature on the sensitization pattern of adult EoE patients and critically discuss the diagnostic and therapeutic tools available. Most EoE patients have elevated total IgE levels in serum and are sensitized to aero- and food
Simon D., Straumann A., Simon H.-U.
openaire   +3 more sources

Muscular and serosal eosinophilic gastritis and enteritis with eosinophilic ascites successfully treated with dupilumab

JPGN Reports, EarlyView.
Abstract Primary eosinophilic gastrointestinal disorders beyond the esophagus (EGIDs) are rare, predominantly Th2‐mediated inflammatory conditions, affecting various segments of the gastrointestinal tract. We report the case of a 12‐year‐old boy with recurrent abdominal pain, peripheral eosinophilia, and progressive gastritis, duodenitis, and enteritis
Almudena Sánchez‐Ramírez, Alejandro García‐Díaz, Ruth García‐Martínez de Bartolomé, Maria Isabel García‐Hidalgo, Maria Luz Cilleruelo, Enriqueta Román‐Riechmann, Carolina Gutiérrez‐Junquera   +6 more
wiley   +1 more source

Association between serum alder‐specific immunoglobulin E positivity and seasonal onset of eosinophilic esophagitis

JGH Open
Background and Aim Pollen exposure may induce seasonal onset of eosinophilic esophagitis. However, whether serum pollen‐specific immunoglobulin E positivity can predict such seasonal eosinophilic esophagitis onset remains unclear.
Akihiro Watanabe, Fumio Tanaka, Akinari Sawada, Yu Nishida, Hirotsugu Maruyama, Masaki Ominami, Koji Otani, Shusei Fukunaga, Shuhei Hosomi, Yasuhiro Fujiwara   +9 more
doaj   +1 more source

Immunopathogenesis of Eosinophilic Esophagitis [PDF]

Digestive Diseases, 2014
<b><i>Background:</i></b> Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus associated with dysphagia in adults and refractory reflux syndromes in children. <b><i>Methods:</i></b> Immunological and genetic approaches have been used to better understand the pathophysiology ...
Simon H.-U., Straumann A.
openaire   +3 more sources

Subthreshold eosinophilia during food impaction may mask eosinophilic esophagitis: A pediatric case series

JPGN Reports, EarlyView.
Abstract To describe the clinical scenario and need for longitudinal follow‐up of pediatric patients presenting with esophageal food impactions (EFIs) regardless of esophageal biopsy eosinophil count. A retrospective chart review was conducted on patients with EFI who underwent endoscopic evaluation from August 2022 to August 2024.
Mark Mahon, Amanda Muir
wiley   +1 more source

Endoscopic diagnosis and management of eosinophilic esophagitis

DEN Open
Eosinophilic esophagitis is a chronic allergic inflammatory disease, and its incidence and prevalence have recently increased. Eosinophilic esophagitis has not become a rare disease; thus, knowledge for diagnosing it is needed in current clinical ...
Fumio Tanaka, Akinari Sawada, Sayaka Tanaka, Kenichi Kohashi, Yasuhiro Fujiwara   +4 more
doaj   +1 more source

Lymphocytic Esophagitis in Nonachalasia Primary Esophageal Motility Disorders: Improved Criteria, Prevalence, Strength of Association, and Natural History. [PDF]

, 2016
Lymphocytic esophagitis (LE) is a histologic pattern with no established clinical correlates in the majority of patients. The goal of this study was to evaluate the association between nonachalasia primary esophageal motility disorders (PEMD) and LE ...
Brickley, Elizabeth B, Gabbard, Scott, Hussain, Zilla H, Lacy, Brian E, Lisovsky, Mikhail, Muller, Kristen E, Parker, Siddhartha, Putra, Juan, Rothstein, Richard   +8 more
core   +1 more source

Dupilumab as an effective therapy for eosinophilic esophagitis in pediatric patients weighing less than 15 kilograms

JPGN Reports, EarlyView.
Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi, Tanaz Danialifar, Thirumazhisai Gunasekaran, Nick Shillingford, Paul Zamiara, Vrinda Bhardwaj, Melinda Braskett   +6 more
wiley   +1 more source

STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic Inflammation [PDF]

, 2016
Allergic inflammation requires the orchestration of altered gene expression in the target tissue and in the infiltrating immune cells. The transcription factor STAT6 is critical in activating cytokine gene expression and cytokine signaling both in the ...
Kaplan, Mark H., Krishnamurthy, Purna
core   +1 more source