Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion +15 more
wiley +1 more source
Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence‐Based Expert Review
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prevalent, heterogeneous inflammatory disease associated with significant morbidity. Systemic corticosteroids (SCS) are commonly prescribed for their anti‐inflammatory effects, but cumulative exposure carries risks, including metabolic, cardiovascular, and skeletal complications.
Andrew Thamboo +28 more
wiley +1 more source
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterized by eosinophilia, asthma, and ear, nose, and throat (ENT) involvement. Although glucocorticoids (GCs) are effective in controlling symptoms, relapses and GC dependence are common. The aim of this study was to develop predictive models for vasculitis
Matthias Papo +35 more
wiley +1 more source
Objective Interstitial lung disease (ILD) can occur in association with antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV‐ILD) or as an isolated entity with positive ANCA (ANCA‐ILD). However, data on the epidemiology and outcomes of these conditions remain limited.
Aglaia Chalkia +18 more
wiley +1 more source
Eosinophilic enteritis: A case for awareness among primary care physicians
Kimitoshi Kubo +2 more
doaj +1 more source
From anaphylaxis to eosinophilic esophagitis during omalizumab treatment in a boy with severe asthma and food allergy: a case report. [PDF]
Jedynak-Wąsowicz U +2 more
europepmc +1 more source
Comprehensive insights into the roles of eosinophils in the mucosal immunity of gastrointestinal tract: defenders, destructors, and modulators. [PDF]
Chen X +9 more
europepmc +1 more source
Benralizumab for anti-tumor necrosis factor-associated eosinophilic gastrointestinal disease in a child with ileal Crohn's: A case report. [PDF]
Dudzik J +3 more
europepmc +1 more source
Circulating eosinophils in patients with hypereosinophilic syndrome have heterogeneous immunophenotypes. [PDF]
Chhiba KD +6 more
europepmc +1 more source

