Results 71 to 80 of about 2,434,139 (259)

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Epidemiology of Angiostrongylus cantonensis and eosinophilic meningitis in the People's Republic of China [PDF]

open access: yes, 2011
Background: Human eosinophilic meningitis is mainly caused by the rat lungworm Angiostrongylus cantonensis, especially in tropical and subtropical regions.
Lv, Shan
core   +1 more source

The expanding spectrum of eosinophilic gastrointestinal disorders: summarizing diagnostic challenges, updated consensus diagnostic criteria, molecular drivers and site-specific histopathological changes [PDF]

open access: yesExploration of Asthma & Allergy
Aim: Eosinophilic gastrointestinal disorders (EGIDs) are chronic inflammatory conditions defined by eosinophilic infiltration of the gastrointestinal tract in the absence of secondary causes.
Nayantrishna Nath   +4 more
doaj   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik   +3 more
wiley   +1 more source

Old disease, new twist

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari   +4 more
wiley   +1 more source

Enhancing diversity, equity, inclusion, and accessibility in eosinophilic gastrointestinal disease research: the consortium for eosinophilic gastrointestinal disease researchers’ journey

open access: yesTherapeutic Advances in Rare Disease, 2023
In response to the social inequities that exist in health care, the NIH-funded Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) recently formed a diversity committee to examine systemic racism and implicit bias in the care and ...
Mirna Chehade   +37 more
doaj   +1 more source

Assessment of eosinophils in gastrointestinal inflammatory disease of dogs [PDF]

open access: yesJournal of Veterinary Internal Medicine, 2018
Abstract Background Accurate identification of eosinophils in the gastrointestinal (GI) tract of dogs with eosinophilic GI disease (EGID) by histological evaluation is challenging. The currently used hematoxylin and eosin (H&E) staining method detects intact eosinophils but does not detect ...
Idil Bastan   +7 more
openaire   +4 more sources

Chronic conditions associated with paediatric onset inflammatory bowel diseases: A population‐based study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Several conditions are associated with inflammatory bowel disease (IBD), including immune‐mediated inflammatory diseases (IMIDs), extraintestinal manifestations (EIMs), and psychiatric disorders. This study aimed to describe at population‐level the comorbidities and their relative burden in paediatric‐onset IBD (pIBD).
Nicolas Richard   +480 more
wiley   +1 more source

Eosinophilic Gastrointestinal Diseases in Childhood

open access: yes, 2019
Eosinophilic gastrointestinal diseases (EGIDs) comprise a group of chronic, inflammatory diseases of the gastrointestinal (GI) tract, that are characterized, clinically, by symptoms related to the dysfunction of the involved segment(s) of the GI tract ...
Papadopoulou, A., Koutri, E.
core   +1 more source

[Anti-interleukin-5 therapy for eosinophilic diseases] [PDF]

open access: yes, 2007
In a number of diseases with eosinophilia, elevated interleukin (IL)-5 levels are detected in the peripheral blood and/or tissues. IL-5 plays an important role in regulating the production, differentiation, recruitment, activation, and survival of ...
Simon, H-U, Simon, D, Braathen, L R
core   +2 more sources

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