Results 1 to 10 of about 5,887,855 (243)

Immunoregulatory mechanisms in parasitic eosinophilic lung disease: the role of IgE immune complexes and NLRC4 inflammasome [PDF]

Frontiers in Immunology
Parasitic eosinophilic lung disease is characterized by eosinophil infiltration and dysregulated immune responses, posing significant challenges due to its complex immunoregulatory mechanisms which remain incompletely understood. This review explores the
Yuanchao Cao, Dingyu Rao, Zongbo Peng, Zihao Chen, Qinghui Xia, Chunfa Xie, Yanglin Fu, Defa Huang, Zuxiong Zhang, Chuan Yao   +9 more
doaj   +3 more sources

Treatments of refractory eosinophilic lung diseases with biologics

Allergology International, 2023
Biologics targeting the molecules associated with type 2 inflammation have significantly improved the outcomes of patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps (CRSwNP).
Koichiro Asano, Yuzo Suzuki, Jun Tanaka, Konomi Kobayashi, Yosuke Kamide   +4 more
doaj   +4 more sources

Chronic Eosinophilic Pneumonia: A Diagnostic Challenge With Atypical Bronchoalveolar Lavage Findings and an Organizing Pneumonia Pattern [PDF]

Respirology Case Reports
Chronic eosinophilic pneumonia (CEP) is a rare eosinophilic lung disease. We report a 61‐year‐old man with asthma who presented with progressive exertional dyspnoea for 2 months and worsening productive cough for 2 weeks.
Yang‐Tai Lin, Wei‐Fan Ou, Sha‐Yen Liang, Yu‐Hsuan Hu, Wan‐Ching Chen, Ming‐Cheng Chan   +5 more
doaj   +2 more sources

Fibrotic chronic eosinophilic pneumonia: from inflammation to fibrosis and therapeutic implications [PDF]

European Respiratory Review
Chronic eosinophilic pneumonia is a rare inflammatory lung disease that typically responds to systemic glucocorticoids but is frequently complicated by relapses and treatment-related toxicity.
Daniele Previtero, Gioele Castelli, Ylenia Padrin, Francesca Scalvenzi, Isabella Ruzzon, Elisabetta Cocconcelli, Mariaenrica Tinè, Elisabetta Balestro, Roberto Padoan, Marco Caminati, Simonetta Baraldo, Paolo Spagnolo, Umberto Semenzato   +12 more
doaj   +2 more sources

Prevalence of blood eosinophilia and its impact on lung functions in stable chronic obstructive pulmonary disease patients [PDF]

Lung India
Background and Objective: Chronic obstructive pulmonary disease (COPD) is marked by persistent airflow limitation. Blood eosinophilia has emerged as a potential biomarker for predicting the risk of exacerbations as well as response to inhaled ...
Gursimran Singh, Komaldeep Kaur, Deepak Aggarwal, Anshu Palta, Chahat Bhatia, Varinder Saini   +5 more
doaj   +2 more sources

Eosinophilic Lung Disease

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2008
Eosinophilic lung diseases represent a group of disorders in which lung infiltrates seen on a chest radiograph, may or may not be accompanied by peripheral blood eosinophilia.
Bhupinder Mann
doaj   +2 more sources

Experience with mepolizumab in adults with severe eosinophilic asthma: a case series from India

Respirology Case Reports, 2021
Severe asthma can be associated with eosinophilic or allergic phenotypes or both. Eosinophilic inflammation is associated with exacerbations and disease severity due to biological activity of interleukin‐5 (IL‐5).
Venkata Nagarjuna Maturu, Priti Meshram, Soumya Das, Ashok Kumar Rajput, Arun Chowdary Kotaru, Bhavesh Kotak, Neeraj Markandeywar, Simran Chhatwal   +7 more
doaj   +1 more source

Classification of non-acute bronchial asthma according to allergy and eosinophil characteristics: a retrospective study

Allergy, Asthma & Clinical Immunology, 2021
Background Investigating the endotypes of the different asthma phenotypes would help disease monitoring, prognosis determination, and improving asthma management standardization.
Yi Jiang, Ruoli An, Li Cheng, Qianru Yue, Hanwei Zhang, Yali Zhang, Xiaomei Kong, Hongxia Ma, Fang Chen, Yufeng Guo   +9 more
doaj   +1 more source

Targeted therapy in eosinophilic chronic obstructive pulmonary disease

ERJ Open Research, 2021
Chronic obstructive pulmonary disease (COPD) is a common and preventable airway disease causing significant worldwide mortality and morbidity. Lifetime exposure to tobacco smoking and environmental particles are the two major risk factors.
Mathieu Fieldes, Chloé Bourguignon, Said Assou, Amel Nasri, Aurélie Fort, Isabelle Vachier, John De Vos, Engi Ahmed, Arnaud Bourdin   +8 more
doaj   +1 more source

Intravenous immunoglobulin treatment stabilizing a patient with Anti-PL7 antisynthetase syndrome with interstitial lung disease and eosinophilic inflammation

Respiratory Medicine Case Reports, 2022
Antisynthetase syndrome (AS) is a rare autoimmune disease characterized by autoantibodies against aminoacyl-transfer RNA synthetase and clinical features which can include interstitial lung disease (ILD).
Soran Peshbahar, Charlotte Hyldgaard, Elisabeth Bendstrup   +2 more
doaj   +1 more source