Results 301 to 310 of about 316,727 (384)
JPGN Reports, EarlyView.Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi +6 more
wiley +1 more source
Eosinophil ETosis and Cancer: Ultrastructural Evidence and Oncological Implications. [PDF]
Cancers (Basel)Caruso R, Caruso V, Rigoli L.
europepmc +1 more source
Journal of Ultrasound in Medicine, EarlyView.Objectives Intra‐amniotic sludge is an independent risk factor for preterm birth. It consists of a biophysical sonographic finding in the amniotic fluid, formed by dense echogenic particles near the cervical internal orifice, due to sterile or infectious inflammatory processes.
Clarissa Chavez Ortiz Roberto +8 more
wiley +1 more source
Non-Invasive Biomarkers for Eosinophilic Esophagitis: Latest Developments and Future Directions. [PDF]
J Clin MedMarulo S +6 more
europepmc +1 more source
Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino +3 more
wiley +1 more source
Drug Hypersensitivity: A Correlation Study From Histopathology to Clinic
JEADV Clinical Practice, EarlyView.ABSTRACT Background Drug hypersensitivity (DH) can present with varied clinical and pathological manifestations that may mislead the referring physician. Available data regarding the concordance between pathological diagnosis and clinical findings in DH are scarce.
Olivier Philip +5 more
wiley +1 more source
Histopathological Aspects of Common Immune Checkpoint Inhibitors Induced Skin Toxicities
JEADV Clinical Practice, EarlyView.ABSTRACT Background The histological characteristics of checkpoint inhibitors‐related adverse events (cirAEs) are not well studied and there are conflicting data regarding their similarities and differences with their idiopathic counterparts. Objectives To investigate the histological characteristics of the most common cirAEs.
Christina Kemanetzi +12 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT A 66‐year‐old man presented with a 5‐year history of recurrent pruritic, waxy folliculocentric papules on his trunk which worsened during winter and minimally responded to selenium sulphide shampoo and topical corticosteroids. Skin biopsy demonstrated a dilated follicular infundibulum containing abundant yeasts and amorphous material with ...
Brandon Tan +2 more
wiley +1 more source