Results 151 to 160 of about 218,961 (294)

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang   +9 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger   +3 more
wiley   +1 more source

Parental Exposure to Nanoplastics and Graphene Oxide Induces Transgenerational Toxicity in Caenorhabditis elegans

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Environmental pollution by emerging contaminants such as nanoplastics (NPs) and graphene oxide (GO) represents a growing threat to global health and ecosystems. This study investigated the effects of parental exposure, both isolated and combined, to 100 μg/L NPs (polystyrene, spherical, 100 nm) and 100 mg/L GO, using Caenorhabditis elegans as ...
Gabriela Corrêa Soares   +6 more
wiley   +1 more source

Computational evaluation of EPA-PC binding to GCase in neuronopathic Gaucher disease. [PDF]

open access: yesCurr Res Struct Biol
Nagori R   +4 more
europepmc   +1 more source

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira   +2 more
wiley   +1 more source

CO2 capture by accelerated weathering of limestone using waste limestone at elevated CO2 concentrations

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Accelerated weathering of limestone (AWL) using waste limestone (WL) for industrially relevant CO2 capture remains underexplored. Previous studies on potable water‐operated AWL have mainly examined idealised conditions, such as the use of high‐purity limestone or relatively low CO2 concentrations, which may not reflect selected ...
Daniel Nyuin Alfred Damu   +3 more
wiley   +1 more source

Accessing Germany's Electronic Patient Record Through Health Insurer-Provided Apps: Qualitative Interview Study. [PDF]

open access: yesJMIR Mhealth Uhealth
May S   +9 more
europepmc   +1 more source

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