Results 1 to 10 of about 1,179 (81)

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl [PDF]

Developmental Dynamics
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the ...
Michael Tolentino, Sarah E. Walker, Gaynor E. Spencer, Robert Carlone   +3 more
exaly   +6 more sources

Ontogeny of ependymoglial cells lining the third ventricle in mice [PDF]

Frontiers in Endocrinology, 2023
IntroductionDuring hypothalamic development, the germinative neuroepithelium gives birth to diverse neural cells that regulate numerous physiological functions in adulthood.MethodsHere, we studied the ontogeny of ependymal cells in the mouse mediobasal hypothalamus using the BrdU approach and publicly available single-cell RNAseq datasets.ResultsWe ...
Lopez-Rodriguez, David, Rohrbach, Antoine, Lanzillo, Marc, Gervais, Manon, Croizier, Sophie, Langlet, Fanny   +5 more
exaly   +8 more sources

Vascular Endothelial Cells Promote Acute Plasticity in Ependymoglial Cells of the Neuroendocrine Brain [PDF]

The Journal of Neuroscience, 2004
Glial and endothelial cells interact throughout the brain to define specific functional domains. Whether endothelial cells convey signals to glia in the mature brain is unknown but is amenable to examination in circumventricular organs. Here we report that purified endothelial cells of one of these organs, the median eminence of the hypothalamus ...
Sandrine, De Seranno, Cecilia, Estrella, Anne, Loyens, Anda, Cornea, Sergio R, Ojeda, Jean-Claude, Beauvillain, Vincent, Prevot   +6 more
exaly   +5 more sources

Ependymoglial cells are critical for cortex regeneration in axolotls [PDF]

Nature Communications
Developing precise targeted cell ablation in the axolotl (Ambystoma mexicanum) is crucial for elucidating the roles or interactions of specific cell types in regeneration and modeling diseases. Here we establish a Nitroreductase (NTR)-based inducible cell ablation system in axolotls.
Sulei Fu, Yan-Yun Zeng, Cheng Peng, Liqun Wang, Yuxian Feng, Kun Wang, Yanmei Liu, Ji-Feng Fei   +7 more
exaly   +5 more sources

Dynamic membrane depolarization is an early regulator of ependymoglial cell response to spinal cord injury in axolotl

Developmental Biology, 2015
Salamanders, such as the Mexican axolotl, are some of the few vertebrates fortunate in their ability to regenerate diverse structures after injury. Unlike mammals they are able to regenerate a fully functional spinal cord after injury. However, the molecular circuitry required to initiate a pro-regenerative response after spinal cord injury is not well
Sabin, Keith, Santos-Ferreira, Tiago, Essig, Jaclyn, Rudasill, Sarah, Echeverri, Karen   +4 more
openaire   +4 more sources

Nitroreductase-mediated cell ablation uncovers the pivotal role of ependymoglial cells in entire cortex regeneration in axolotls

Abstract Developing precise targeted cell ablation in the axolotl (Ambystoma mexicanum) is crucial for elucidating the roles or interactions of specific cell types in regeneration and modeling diseases. Here we establish a Nitroreductase (NTR)-based inducible cell ablation system in axolotls.
Ji-Feng Fei, Sulei Fu, Yan-Yun Zeng, Cheng Peng, Liqun Wang, Yuxian Feng, Kun Wang, Yanmei Liu   +7 more
openaire   +1 more source

High-resolution single-cell analysis paves the cellular path for brain regeneration in salamanders. [PDF]

Cell Regen, 2022
Yin B, Li X, Lin G, Wang H.
europepmc   +1 more source

MicroRNAs in Tissue Regeneration: Lessons from Animal Models. [PDF]

Int J Mol Sci
Walker SE, Piazza A, Carlone RL, Spencer GE.   +3 more
europepmc   +1 more source

High-dimensional co-expression network analysis reveals persistent TRH gene expression throughout axolotl telencephalon regeneration. [PDF]

Front Bioinform
Gómez-Morales I, Mendizabal-Ruiz AP, Morales JA, Romero-Gutiérrez T.   +3 more
europepmc   +1 more source

A spatial transcriptomics comparison of the adult versus metamorphosed axolotl brain. [PDF]

Sci Data
Wang S, Fu S, Liu X, Zeng YY, Zhang L, Zhang N, Dai X, Li H, Gu Y, Wei X, Fei JF, Liu Y.   +11 more
europepmc   +1 more source