Results 21 to 30 of about 7,866 (212)

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Energy Poverty in China: Measurement, Regional Inequality, and Dynamic Evolution

Energies
Against the backdrop of China’s transition from the eradication of absolute poverty toward the pursuit of common prosperity, equitable access to energy has become an increasingly important policy concern.
Zhiyuan Gao, Ziying Jia, Chuantong Zhang, Shengbo Gao, Xinyi Yang, Yu Hao   +5 more
doaj   +1 more source

Limit behavior of an oscillating thin layer

Electronic Journal of Differential Equations, 2006
We study the limit behavior of a thermal problem, of a containing structure, an oscillating thin layer of thickness and conductivity depending of $varepsilon$.
Abdelaziz Ait Moussa, Jamal Messaho
doaj  

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Epigenetic and mitoepigenetic regulation in cancer and therapeutic perspectives

Frontiers in Pharmacology
Epigenetic modifications on nuclear and mitochondrial DNA constitute key regulatory layers influencing the transcriptional, metabolic, and phenotypic adaptability of cancer cells.
Selcen Celik-Uzuner, Ihsan Nalkiran, Ugur Uzuner, Ugur Uzuner, Hatice Sevim Nalkiran   +4 more
doaj   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Evaluation of the epi-convergence

, 2005
The paper presents an equivalent characterization of the epi-convergence of lower semicontinuous functions. The proposed ‘measures’ naturally estimate the distance between optimal values of two optimization programs. A comparison of optimal solutions is more complex.
openaire   +2 more sources

Dielectric Elastomer Actuators as Safe and Effective Tools for Mechanostimulation of Human Cells

Advanced Intelligent Systems, EarlyView.
Replicating physiological forces is crucial for realistic cell models. Dielectric elastomer actuators (DEAs) offer a soft alternative, though their high voltages raised toxicity concerns. We demonstrate that DEA stimulation causes no cell damage, cell death or cell‐cycle disruption, while activating mechanosensitive responses.
Simon Holzer, Chaimae Bahou, Noe Syfrig, Katia Monastyrskaya, Yoan Civet, Ali Hashemi Gheinani, Yves Perriard   +6 more
wiley   +1 more source

The cranial, mandibular, and hyoid anatomy of softshell turtles (Trionychidae): A revised character list for phylogenetic analysis

The Anatomical Record, EarlyView.
Abstract Softshell turtles (Pan‐Trionychidae) are an early branching clade of hidden‐necked turtles (Cryptodira) with a rich fossil record extending back to the Early Cretaceous. The evolutionary history of softshell turtles is still unresolved because of their conservative morphology combined with high levels of polymorphism related to morphological ...
Léa C. Girard, Walter G. Joyce
wiley   +1 more source

Accurate Agarwood Oil Quality Determination: A Breakthrough With Artificial Neural Networks and the Levenberg- Marquardt Algorithm

IEEE Access
The agarwood oil quality has been divided into four grades, including low, medium-low, medium-high, and high, and has been thoroughly examined in this manuscript.
Siti Mariatul Hazwa Mohd Huzir, Anis Hazirah 'Izzati Hasnu Al-Hadi, Zakiah Mohd Yusoff, Nurlaila Ismail, Mohd Nasir Taib   +4 more
doaj   +1 more source