Results 31 to 40 of about 735,785 (220)

4th International LIS-EPI meeting: una mirada al futuro de la información [PDF]

open access: yes, 2010
Report on the 4th International LIS-EPI Meeting which was held in Valencia in November 2009, under the title “Information in 2015”. The topics covered were the future of information and libraries, Rich Internet Applications (RIAs), free software in ...
Arroyo Vázquez, Natalia   +2 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

M-Convergence, et régularité des martingales multivoques: Epi-martingales [PDF]

open access: yes, 1990
In this work, the fundamental convergence theorems for multivalued martingales are established in Mosco's sense.
Choukairi-Dini, Ahmed
core   +1 more source

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

open access: yesAdvanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge   +13 more
wiley   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

open access: yesAdvanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin   +7 more
wiley   +1 more source

crricci/Epi-Econ: 1.0

open access: yes, 2023
Full Changelog: https://github.com/crricci/Epi-Econ/commits/1.
Cristiano Ricci
core   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

open access: yesAdvanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne   +15 more
wiley   +1 more source

Multi-omics based and AI-driven drug repositioning for epigenetic therapy in female malignancies

open access: yesJournal of Translational Medicine
Histone post-translational modifications (PTMs) have long been recognized as critical regulators of chromatin dynamics and gene expression, with aberrations in these processes driving tumorigenesis, immune escape, metastasis, and therapy resistance ...
Annamaria Salvati   +14 more
doaj   +1 more source

Accurate Agarwood Oil Quality Determination: A Breakthrough With Artificial Neural Networks and the Levenberg- Marquardt Algorithm

open access: yesIEEE Access
The agarwood oil quality has been divided into four grades, including low, medium-low, medium-high, and high, and has been thoroughly examined in this manuscript.
Siti Mariatul Hazwa Mohd Huzir   +4 more
doaj   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

open access: yesAdvanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei   +17 more
wiley   +1 more source

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