Results 131 to 140 of about 919,101 (335)
What to consider when pseudohypoparathyroidism is ruled out: iPPSD and differential diagnosis
BMC Medical Genetics, 2018 Background Pseudohypoparathyroidism (PHP) is a rare disease whose phenotypic features are rather difficult to identify in some cases. Thus, although these patients may present with the Albright’s hereditary osteodystrophy (AHO) phenotype, which is ...
Arrate Pereda +3 more
doaj +1 more source
EPI Update, July 20, 2007 [PDF]
, 2007 Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
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Advanced Science, EarlyView.ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin +9 more
wiley +1 more source
High-Order Time Discretization of The Wave Equation by Nabla-P Scheme.*
ESAIM: Proceedings and Surveys, 2014 High-order Discontinuous Galerkin Methods (DGM) are now routinely used for simulation of wave propagation, especially for geophysical applications.
Barucq Hélène +3 more
doaj +1 more source
EPI Update, April 3, 2009 [PDF]
, 2009 Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
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Advanced Science, EarlyView.Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian +11 more
wiley +1 more source
EPI Update, August 6, 2010 [PDF]
, 2010 Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
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Advanced Science, EarlyView.Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source
Advanced Science, EarlyView.This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang +5 more
wiley +1 more source
EPI Update, May 29, 2009 [PDF]
, 2009 Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...
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