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Maternal vgll4a regulates zebrafish epiboly through Yap1 activity [PDF]

open access: goldFrontiers in Cell and Developmental Biology
Gastrulation in zebrafish embryos commences with the morphogenetic rearrangement of blastodermal cells, which undergo a coordinated spreading from the animal pole to wrap around the egg at the vegetal pole. This rearrangement, known as epiboly, relies on
Carlos Camacho-Macorra   +9 more
doaj   +4 more sources

Transcriptome Analysis Suggested Striking Transition Around the End of Epiboly in the Gene Regulatory Network Downstream of the Oct4‐Type POU Gene in Zebrafish Embryos [PDF]

open access: hybridDevelopment, Growth &Differentiation, Volume 67, Issue 5, Page 245-269, June 2025.
Zebrafish pou5f3 encodes a Class V POU transcription factor, Pou5f3, which regulates various developmental processes, including neurogenesis and brain formation.
Masa‐Aki Ikeda   +6 more
semanticscholar   +4 more sources

Multiple asters organize the yolk microtubule network during dclk2-GFP zebrafish epiboly [PDF]

open access: goldScientific Reports, 2022
It is known that the organization of microtubule (MT) networks in cells is orchestrated by subcellular structures named MT organizing centers (MTOCs). In this work, we use Light Sheet Fluorescence and Confocal Microscopy to investigate how the MT network
Maria Marsal   +3 more
doaj   +3 more sources

The Adaptor Protein Lurap1 Is Required for Cell Cohesion during Epiboly Movement in Zebrafish [PDF]

open access: goldBiology, 2021
Cell adhesion and polarized cellular behaviors play critical roles in a wide variety of morphogenetic events. In the zebrafish embryo, epiboly represents an important process of epithelial morphogenesis that involves differential cell adhesion and ...
Ji-Tong Li   +4 more
doaj   +3 more sources

Investigation of Zebrafish Embryo Membranes at Epiboly Stage through Electrorotation Technique [PDF]

open access: yesMembranes, 2023
A preliminary exploration of the physiology and morphology of the zebrafish embryo (ZFE) during the late-blastula and early-gastrula stages through its electrical properties was performed, applying the electrorotation (ROT) technique.
Aránzazu Sanchis-Otero   +4 more
doaj   +3 more sources

Actin-mediated endocytosis in the E-YSL helps drive epiboly in zebrafish [PDF]

open access: hybridZygote (Cambridge. Print), 2023
In zebrafish, a punctate band of F-actin is reported to develop in the external yolk syncytial layer (E-YSL) during the latter part of epiboly in zebrafish embryos.
Jackie Cheng   +2 more
openalex   +2 more sources

Rab5ab-Mediated Yolk Cell Membrane Endocytosis Is Essential for Zebrafish Epiboly and Mechanical Equilibrium During Gastrulation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Morphogenesis in early embryos demands the coordinated distribution of cells and tissues to their final destination in a spatio-temporal controlled way.
Maria Marsal   +3 more
doaj   +2 more sources

Syne2b/Nesprin-2 Is Required for Actin Organization and Epithelial Integrity During Epiboly Movement in Zebrafish

open access: yesFrontiers in Cell and Developmental Biology, 2021
Syne2b/nesprin-2 is a giant protein implicated in tethering the nucleus to the cytoskeleton and plays an important role in maintaining cellular architecture.
Yu-Long Li   +5 more
doaj   +2 more sources

Maternal vgll4a promotes blastoderm cohesion enabling yap1-mediated mechano-transduction during zebrafish epiboly [PDF]

open access: greenbioRxiv, 2020
Cellular cohesion provides tissue tension, which is then sensed by the cytoskeleton and decoded by the activity of mechano-transducers, such as the transcriptional cofactor Yap1, thereby enabling morphogenetic responses in multi-cellular organisms.
Carlos Camacho-Macorra   +3 more
openalex   +2 more sources

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly

open access: yeseLife, 2020
The glucose-sensing Mondo pathway regulates expression of metabolic genes in mammals. Here, we characterized its function in the zebrafish and revealed an unexpected role of this pathway in vertebrate embryonic development.
Meltem Weger   +15 more
doaj   +2 more sources

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