Results 11 to 20 of about 3,580 (190)
Niclosamide Induces Epiboly Delay During Early Zebrafish Embryogenesis [PDF]
Toxicological Sciences, 2018 Niclosamide is an antihelminthic drug used worldwide for the treatment of tapeworm infections. Recent drug repurposing screens have revealed that niclosamide exhibits diverse mechanisms of action and, as a result, demonstrates promise for a number of ...
Sara M.F. Vliet +2 more
semanticscholar +6 more sources
Zebrafish
BMC Research Notes, 2009 Background The zebrafish, Danio rerio, possesses the paralogous genes aplnra and aplnrb that are duplicates of an ancestral orthologue of the human APLNR gene encoding a G-protein coupled receptor that binds the peptide ligand APELIN and is required for ...
Lardelli Michael +2 more
doaj +5 more sources
Spatiotemporal characterization of dynamic epithelial filopodia during zebrafish epiboly [PDF]
Developmental Dynamics, 2019 During zebrafish epiboly, the embryonic cell mass, or blastoderm, spreads to enclose the yolk cell. The blastoderm consists of an outer epithelial sheet, the enveloping layer (EVL), and the underlying deep cell layer (DEL). Studies have provided insights
Nathan Elliott Rutherford +2 more
semanticscholar +4 more sources
Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly [PDF]
International Journal of Biological Sciences, 2017 During embryonic gastrulation, coordinated cell movements occur to bring cells to their correct position. Among them, epiboly produces the first distinct morphological changes, which is essential for the early development of zebrafish.
Qingrui Sun +5 more
semanticscholar +4 more sources
Contractility, Differential Tension and Membrane Removal direct zebrafish Epiboly Biomechanics [PDF]
American Zoologist, 2017 Precise tissue remodeling during development is essential for shaping embryos and for optimal organ function. Epiboly is an early gastrulation event by which the blastoderm expands around the yolk to engulf it.
María Marsal, Enrique Martı́n-Blanco
semanticscholar +4 more sources
Zebrafish epiboly: Spreading thin over the yolk [PDF]
Developmental Dynamics, 2015 Tissue thinning and spreading, a morphogenetic movement termed epiboly, is used widely during animal development. In zebrafish, epiboly is a prominent cell movement during gastrulation, whereby a squamous epithelium (the enveloping layer), a multi‐layer of loosely packed cells (the deep cells), and a yolk nuclear syncytium (the yolk syncytial layer ...
Ashley E.E. Bruce
semanticscholar +4 more sources
A cargo model of yolk syncytial nuclear migration during zebrafish epiboly [PDF]
Development, 2018 In teleost fish, the multinucleate yolk syncytial layer functions as an extraembryonic signaling center to pattern mesendoderm, coordinate morphogenesis and supply nutrients to the embryo. External yolk syncytial nuclei (e-YSN) undergo microtubule dependent movements that distribute the nuclei over the large yolk mass. How e-YSN migration proceeds, and
Zhonghui Fei +7 more
semanticscholar +4 more sources
Polarized Cortical Tension drives Zebrafish Epiboly Movements [PDF]
The EMBO Journal, 2015 SUMMARYThe physical principles underlying the biomechanics of morphogenetic processes are largely unknown. Epiboly is an essential embryonic event in which three distinct tissues coordinate to direct the expansion of the blastoderm. How and where forces are generated during epiboly and how these are globally coupled remains elusive.
Amayra Hernández‐Vega +8 more
semanticscholar +7 more sources
In preprints: expanded insight into epithelial spreading during zebrafish epiboly [PDF]
DevelopmentGuan Dikai, Ashley E.E. Bruce
semanticscholar +4 more sources
Stage-specific transcriptomic and DNA methylation responses to triploidy in European sea bass embryos and larvae [PDF]
BMC GenomicsBackground Polyploidy, the condition of having more than two chromosome sets, is relatively common in plants but rare in animals, largely due to reproductive challenges associated with altered chromosome numbers.
S. Beato +3 more
doaj +2 more sources