Results 11 to 20 of about 3,428 (174)

Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

open access: goldBiology Open, 2013
Summary Fetal alcohol spectrum disorder (FASD) occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic birth defects that include craniofacial, neural and cardiac defects.
Swapnalee Sarmah   +14 more
doaj   +2 more sources

Testing biological actions of medicinal plants from northern Vietnam on zebrafish embryos and larvae: Developmental, behavioral, and putative therapeutical effects. [PDF]

open access: yesPLoS ONE, 2023
Evaluating the risks and benefits of using traditional medicinal plants is of utmost importance for a huge fraction of the human population, in particular in Northern Vietnam. Zebrafish are increasingly used as a simple vertebrate model for testing toxic
My Hanh Tran   +12 more
doaj   +2 more sources

Gastrulation Screening to Identify Anti-metastasis Drugs in Zebrafish Embryos [PDF]

open access: yesBio-Protocol, 2022
Few models exist that allow for rapid and effective screening of anti-metastasis drugs. Here, we present a drug screening protocol utilizing gastrulation of zebrafish embryos for identification of anti-metastasis drugs.
Joji Nakayama   +2 more
doaj   +2 more sources

Stage‐by‐stage exploration of normal embryonic development in the Arabian killifish, Aphanius dispar [PDF]

open access: yesDevelopmental Dynamics, Volume 254, Issue 5, Page 380-395, May 2025.
Abstract Background Arabian killifish, Aphanius dispar, lives in marine coastal areas of the Middle East, as well as in streams that experience a wide range of salinities and temperatures. It has been used as a mosquito control agent and for studying the toxicities of environmental pollutants. A.
Amena Alsakran   +5 more
wiley   +2 more sources

Essential Oils Produce Developmental Toxicity in Zebrafish Embryos and Cause Behavior Changes in Zebrafish Larvae [PDF]

open access: yesBiomedicines, 2023
Essential oils have gained significant popularity in various industries due to their biological properties, but their potential toxic effects on living organisms have been poorly investigated. This study aimed to evaluate the effects of lemongrass, thyme,
Ivanildo Inacio da Silva   +3 more
doaj   +2 more sources

Modeling Epithelial Morphogenesis and Cell Rearrangement during Zebrafish Epiboly: Tissue Deformation, Cell-Cell Coupling, and the Mechanical Response to Stress

open access: greenbioRxiv
Morphogenesis in early development involves complex and extreme deformations in response to intra- and intercellular forces. Zebrafish epiboly, the spreading of the blastoderm to cover and engulf the large yolk cell, is a key early event that sets the ...
Sharon B. Minsuk   +4 more
openalex   +2 more sources

Gdf11 regulates left‐right asymmetry development through TGF‐β signal [PDF]

open access: yesCell Proliferation, Volume 58, Issue 3, March 2025.
Gdf11 forms a heterodimer with Spaw, activating the activin receptor and phosphorylating Smad2/3. This process DFC proliferation, subsequently activates the expression of foxj1a and its target genes, promoting cilia formation. Abstract During the embryonic developmental stage in vertebrates, internal organs are arranged along the left–right axis ...
Wantao Yao   +4 more
wiley   +2 more sources

The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development.

open access: goldPLoS Genetics, 2009
The aberrant expression of the transmembrane protein EpCAM is associated with tumor progression, affecting different cellular processes such as cell-cell adhesion, migration, proliferation, differentiation, signaling, and invasion.
Krasimir Slanchev   +6 more
doaj   +2 more sources

Epiboly generates the epidermal basal monolayer and spreads the nascent mammalian skin to enclose the embryonic body [PDF]

open access: greenJournal of Cell Science, 2016
Epiboly is a morphogenetic process that is employed in the surface ectoderm of anamniotes during gastrulation to cover the entire embryo. We propose here that mammals also utilise this process to expand the epidermis and enclose the body cavity and ...
Eleni Panousopoulou   +4 more
semanticscholar   +3 more sources

The Bcl-2 Homolog Nrz Inhibits Binding of IP 3 to Its Receptor to Control Calcium Signaling During Zebrafish Epiboly

open access: greenScience Signaling, 2014
Phosphorylation of a Bcl-2–like protein allows calcium signals needed for the early stages of development. Nrz-IP3 Tug-of-War During early development of zebrafish, cells migrate over the yolk in a process known as epiboly.
Benjamin Bonneau   +6 more
openalex   +3 more sources

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