Ecotoxicology and Environmental SafetyPer- and polyfluoroalkyl substances (PFAS) persistence within environmental media has led to ubiquitous exposure within humans and wildlife. We previously found that exposure of zebrafish embryos to perfluorooctanesulfonamide (PFOSA) from 0.75 to 6 h ...
John Hoang +7 more
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Essential Oils Produce Developmental Toxicity in Zebrafish Embryos and Cause Behavior Changes in Zebrafish Larvae [PDF]
Biomedicines, 2023 Essential oils have gained significant popularity in various industries due to their biological properties, but their potential toxic effects on living organisms have been poorly investigated. This study aimed to evaluate the effects of lemongrass, thyme,
Ivanildo Inacio da Silva +3 more
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Non-directional radial intercalation dominates deep cell behavior during zebrafish epiboly [PDF]
Biology Open, 2013 Summary Epiboly is the first coordinated cell movement in most vertebrates and marks the onset of gastrulation. During zebrafish epiboly, enveloping layer (EVL) and deep cells spread over the vegetal yolk mass with a concomitant thinning of the deep cell
Robert Bensch +3 more
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Testing biological actions of medicinal plants from northern Vietnam on zebrafish embryos and larvae: Developmental, behavioral, and putative therapeutical effects. [PDF]
PLoS ONE, 2023 Evaluating the risks and benefits of using traditional medicinal plants is of utmost importance for a huge fraction of the human population, in particular in Northern Vietnam. Zebrafish are increasingly used as a simple vertebrate model for testing toxic
My Hanh Tran +12 more
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Dorsal forerunner cells transmit epiboly forces to extend the zebrafish notochord [PDF]
bioRxivConvergence and extension (C&E) cell movements promote anteroposterior axis extension and narrow both neuroectodermal and mesodermal tissues during gastrulation.
Christopher Small, Margot Williams
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Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebrafish epiboly [PDF]
Nature Cell Biology, 2013 Epithelial spreading is a common and fundamental aspect of various developmental and disease-related processes such as epithelial closure and wound healing.
Pedro Campinho +5 more
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bioRxivMorphogenesis in early development involves complex and extreme deformations in response to intra- and intercellular forces. Zebrafish epiboly, the spreading of the blastoderm to cover and engulf the large yolk cell, is a key early event that sets the ...
Sharon B. Minsuk +4 more
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PLoS Genetics, 2009 The aberrant expression of the transmembrane protein EpCAM is associated with tumor progression, affecting different cellular processes such as cell-cell adhesion, migration, proliferation, differentiation, signaling, and invasion.
Krasimir Slanchev +6 more
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Maternal vgll4a promotes blastoderm cohesion enabling yap1-mediated mechano-transduction during zebrafish epiboly [PDF]
bioRxiv, 2020 Cellular cohesion provides tissue tension, which is then sensed by the cytoskeleton and decoded by the activity of mechano-transducers, such as the transcriptional cofactor Yap1, thereby enabling morphogenetic responses in multi-cellular organisms.
Carlos Camacho-Macorra +3 more
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Control of tissue flows and embryo geometry in avian gastrulation [PDF]
Nature CommunicationsEmbryonic tissues undergo coordinated flows during avian gastrulation to establish the body plan. Here, we elucidate how the interplay between embryonic and extraembryonic tissues affects the chick embryo’s size and shape.
Guillermo Serrano Nájera +4 more
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