Results 41 to 50 of about 3,580 (190)

Apolipoprotein C1 regulates epiboly during gastrulation in zebrafish [PDF]

open access: hybridScience China Life Sciences, 2013
Apolipoprotein C1 (Apoc1) is associated with lipoprotein metabolism, but its physiological role during embryogenesis is largely unknown. We reveal a new function of Apoc1b, a transcript isoform of Apoc1, in epiboly during zebrafish gastrulation. Apoc1b is expressed in yolk syncytial layers and in deep cells of the ventral and lateral region of the ...
Yang Wang   +4 more
openalex   +3 more sources

Dynamin-dependent maintenance of epithelial integrity is essential for zebrafish epiboly [PDF]

open access: bronzeBioArchitecture, 2014
Epiboly, the thinning and spreading of one tissue over another, is a widely employed morphogenetic movement that is essential for the development of many organisms. In the zebrafish embryo, epiboly describes the coordinated vegetal movement of the deep cells, enveloping layer (EVL) and yolk syncytial layer (YSL) to engulf the yolk cell.
Stéphanie Lepage, Ashley E.E. Bruce
openalex   +3 more sources

Gastrulation Screening to Identify Anti-metastasis Drugs in Zebrafish Embryos

open access: yesBio-Protocol, 2022
Few models exist that allow for rapid and effective screening of anti-metastasis drugs. Here, we present a drug screening protocol utilizing gastrulation of zebrafish embryos for identification of anti-metastasis drugs.
Joji Nakayama   +2 more
doaj   +1 more source

Stage-by-stage exploration of normal embryonic development in the Arabian killifish, Aphanius dispar. [PDF]

open access: yesDev Dyn
Abstract Background Arabian killifish, Aphanius dispar, lives in marine coastal areas of the Middle East, as well as in streams that experience a wide range of salinities and temperatures. It has been used as a mosquito control agent and for studying the toxicities of environmental pollutants. A.
Alsakran A   +5 more
europepmc   +2 more sources

Fishing for drugs

open access: yeseLife, 2022
Screening for drugs that disrupt embryonic development in zebrafish can help identify treatments that suppress metastasis.
Chinyere Kemet, Emily Hill, Hui Feng
doaj   +1 more source

The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium

open access: yeseLife, 2021
In emerging epithelial tissues, cells undergo dramatic rearrangements to promote tissue shape changes. Dividing cells remain interconnected via transient cytokinetic bridges.
Patrick Morley Willoughby   +11 more
doaj   +1 more source

Zebrafish as a Model for Fetal Alcohol Spectrum Disorders

open access: yesFrontiers in Pharmacology, 2021
In this review, we will discuss zebrafish as a model for studying mechanisms of human fetal alcohol spectrum disorders (FASDs). We will overview the studies on FASDs so far and will discuss with specific focus on the mechanisms by which alcohol alters ...
Amena Alsakran   +2 more
doaj   +1 more source

O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development [PDF]

open access: hybridBMC Developmental Biology, 2009
Abstract Background The post-translational addition of the monosaccharide O-linked β-N-acetylglucosamine (O-GlcNAc) regulates the activity of a wide variety of nuclear and cytoplasmic proteins. The enzymes O-GlcNAc Transferase (Ogt) and O-GlcNAcase (Oga) catalyze, respectively, the attachment and removal of O-GlcNAc ...
Danielle M. Webster   +7 more
openalex   +4 more sources

Erratum to: Desmosomal cadherins in zebrafish epiboly and gastrulation [PDF]

open access: hybridBMC Developmental Biology, 2014
Alexander Goonesinghe   +3 more
  +5 more sources

Home - About - Disclaimer - Privacy