Results 41 to 50 of about 3,428 (174)
A novel role for MAPKAPK2 in morphogenesis during zebrafish development.
PLoS Genetics, 2009 One of the earliest morphogenetic processes in the development of many animals is epiboly. In the zebrafish, epiboly ensues when the animally localized blastoderm cells spread, thin over, and enclose the vegetally localized yolk.
Beth A Holloway +8 more
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Non-directional radial intercalation dominates deep cell behavior during zebrafish epiboly
Biology Open, 2013 Summary Epiboly is the first coordinated cell movement in most vertebrates and marks the onset of gastrulation. During zebrafish epiboly, enveloping layer (EVL) and deep cells spread over the vegetal yolk mass with a concomitant thinning of the deep cell
Robert Bensch +3 more
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Scientific Reports, 2021 During gastrulation of the zebrafish embryo, the cap of blastoderm cells organizes into the axial body plan of the embryo with left–right symmetry and head–tail, dorsal–ventral polarities.
Dipanjan Bhattacharya +4 more
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eLife, 2021 Metastasis is responsible for approximately 90% of cancer-associated mortality but few models exist that allow for rapid and effective screening of anti-metastasis drugs.
Joji Nakayama +6 more
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Progesterone modulates microtubule dynamics and epiboly progression during zebrafish gastrulation
Developmental Biology, 2017 Stephanie Eckerle +4 more
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Molecules, 2018 By using a zebrafish embryo model to guide the chromatographic fractionation of antimitotic secondary metabolites, seven podophyllotoxin-type lignans were isolated from a hydroalcoholic extract obtained from the steam bark of Bursera fagaroides.
Mayra Antúnez-Mojica +6 more
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eLife, 2017 Sphingosine-1-phosphate (S1P) is generated through phosphorylation of sphingosine by sphingosine kinases (Sphk1 and Sphk2). We show that sphk2 maternal-zygotic mutant zebrafish embryos (sphk2MZ) display early developmental phenotypes, including a delay ...
Karen Mendelson +6 more
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Regionalized tissue fluidization is required for epithelial gap closure during insect gastrulation
Nature Communications, 2020 The mechanics of embryonic tissue spreading over spherical eggs is not fully understood. Here, the authors show that during gastrulation in the red flour beetle, extraembryonic tissue epiboly is facilitated by local actomyosin-mediated fluidization of ...
Akanksha Jain +12 more
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Frontiers in Systems Biology, 2022 Embryonic development is a complex phenomenon that integrates genetic regulation and biomechanical cellular behaviors. However, the relative influence of these factors on spatiotemporal morphogen distributions is not well understood.
Linlin Li +9 more
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