Results 51 to 60 of about 3,428 (174)

Epiboly in zebrafish requires reactive oxygen species produced by NADPH oxidases for the regulation of vesicular trafficking

bioRxiv
Epiboly is the first morphogenetic cell movement that occurs at the onset of gastrulation in zebrafish. During epiboly, the blastoderm thins out and spreads cells over the massive yolk cell.
Arlen Ramírez-Corona, Brenda Reza-Medina, Denhi Schnabel, H. Lomelí, E. Salas-Vidal   +4 more
semanticscholar   +1 more source

A vertebrate-specific Chp-PAK-PIX pathway maintains E-cadherin at adherens junctions during zebrafish epiboly. [PDF]

PLoS ONE, 2010
BACKGROUND: In early vertebrate development, embryonic tissues modulate cell adhesiveness and acto-myosin contractility to correctly orchestrate the complex processes of gastrulation.
Hwee Goon Tay, Yuen Wai Ng, Ed Manser
doaj   +1 more source

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish

Developmental Dynamics, EarlyView.
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan, Travis K. Johnson, Zachary Di Pastena, Jarrad N. Fuller, Lee B. Miles, Sebastian Dworkin   +5 more
wiley   +1 more source

Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish

Epigenetics & Chromatin, 2020
Background Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This susceptibility may in part be caused by changes to the epigenetic landscape which consequently affect gene ...
Marjo J. den Broeder, Jarle Ballangby, Leonie M. Kamminga, Peter Aleström, Juliette Legler, Leif C. Lindeman, Jorke H. Kamstra   +6 more
doaj   +1 more source

Climate‐Resilient Aquaculture: Recirculatory Aquaculture Systems–Based Seed Production for Heteropneustes fossilis in Bangladesh

Aquaculture, Fish and Fisheries, Volume 5, Issue 3, June 2025.
ABSTRACT Aquaculture in Bangladesh heavily relies on hatchery‐produced seeds but encounters climate change challenges. In an experimental study, two distinct recirculatory aquaculture systems (RAS) were employed: large‐RAS (LRAS) and mini‐RAS (MRAS).
Balaram Mahalder, Md. Naim Mahmud, Mst. Rabia Basori, Most. Israt Jahan Seba, Mst. Afrina Bintay Harun Shammi, Mohammad Abu Baker Siddique, A. K. Shakur Ahammad, Mohammad Mahfujul Haque   +7 more
wiley   +1 more source

Soft Modular Robotic Cubes: Toward Replicating Morphogenetic Movements of the Embryo. [PDF]

PLoS ONE, 2017
In this paper we present a new type of simple, pneumatically actuated, soft modular robotic system that can reproduce fundamental cell behaviors observed during morphogenesis; the initial shaping stage of the living embryo.
Andrea Vergara, Yi-Sheng Lau, Ricardo-Franco Mendoza-Garcia, Juan Cristóbal Zagal   +3 more
doaj   +1 more source

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]

Open Biology, 2020
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung, Tsung-Ming Chen, Jing-Ping Lin, Yu-Ling Tai, Tang-Long Shen, Shyh-Jye Lee   +5 more
doaj   +1 more source

Genetic Mechanism That Defines the Characteristic Neurogenesis Patterns in the Neural Plate Using Hes/her Genes During Early Vertebrate Development

genesis, Volume 63, Issue 3, June 2025.
ABSTRACT In the early zebrafish neural plate, proneural cluster domains are defined by surrounding neural progenitor pools (NPPs), generating primary neurogenesis patterns. In each NPP, several Notch‐independent Hes/her‐type genes are expressed in distinct manners.
Takero Ohyanagi, Hiroki Tokizaki, Takehisa Sato, Momo Tsuruoka, Kyo Yamasu   +4 more
wiley   +1 more source

Spatiotemporal characterization of dynamic epithelial filopodia during zebrafish epiboly

Developmental Dynamics, 2019
During zebrafish epiboly, the embryonic cell mass, or blastoderm, spreads to enclose the yolk cell. The blastoderm consists of an outer epithelial sheet, the enveloping layer (EVL), and the underlying deep cell layer (DEL). Studies have provided insights
Nathan E Rutherford, Alexander H Wong, A. Bruce   +2 more
semanticscholar   +1 more source

De Novo Variant in GBX1 Gene Associated With Developmental Delay and Focal Epilepsy

Molecular Genetics &Genomic Medicine, Volume 13, Issue 6, June 2025.
We first identified an association between the GBX1 gene variant and focal epilepsy, and observed related phenotypes in the gbx1‐Cas9 zebrafish model. ABSTRACT Background The gastrulation brain homeobox (Gbx) family, including GBX1 and GBX2, is crucial for hindbrain development and contributes to the morphogenesis of the midbrain–hindbrain boundary ...
Bingbing Zhang, Xiaohua Li, Xiao Qian, Jihong Tang   +3 more
wiley   +1 more source