Results 81 to 90 of about 3,580 (190)

Bmp suppression in mangrove killifish embryos causes a split in the body axis. [PDF]

PLoS ONE, 2014
Bone morphogenetic proteins (Bmp) are major players in the formation of the vertebrate body plan due to their crucial role in patterning of the dorsal-ventral (DV) axis.
Sulayman Mourabit, Michael W Moles, Emma Smith, Ronny van Aerle, Tetsuhiro Kudoh   +4 more
doaj   +1 more source

Growth and Developmental Processes Alternate During Larval Development of Atlantic Herring

Evolution &Development, Volume 27, Issue 4, December 2025.
During their development, fish pass through a series of developmental processes advancing, for example, their physiological and locomotive abilities. Gene expression analysis combined with histological and morphological analysis of Atlantic herring in different larval life stages showed two major growth periods in larval herring development alternating
Vivian Fischbach, George P. Franz, Timo Moritz, Daniela Ohde, Philipp Thieme, Paul Kotterba, Patrick Polte, Bianka Grunow   +7 more
wiley   +1 more source

hdac4 mediates perichondral ossification and pharyngeal skeleton development in the zebrafish [PDF]

PeerJ, 2019
Background Histone deacetylases (HDACs) are epigenetic factors that function to repress gene transcription by removing acetyl groups from the N-terminal of histone lysines.
April DeLaurier, Cynthia Lizzet Alvarez, Kali J Wiggins   +2 more
doaj   +2 more sources

Molecular characteristics of the edge cells responsible for expansion of the chick embryo on the vitelline membrane

Open Biology, 2022
During early avian development, only a narrow band of cells (the edge cells, also called ‘margin of overgrowth’) at the rim of the embryo is responsible for blastoderm expansion by crawling over the vitelline membrane (VM) to cover the whole egg yolk in ...
Hyung Chul Lee, Yara Fadaili, Claudio D. Stern   +2 more
doaj   +1 more source

Photopharmacology beyond azobenzene photoswitches

Responsive Materials, Volume 3, Issue 4, November 2025.
Photopharmacology is advancing beyond traditional azobenzene photoswitches by developing new photoresponsive molecules with improved thermal stability, efficiency, and long‐wavelength activation, enhancing their potential for precise biomedical applications.
Huichao Guo, Jinghong Dai, Long Deng, Zhiwei Zhang, He Tian, Junji Zhang   +5 more
wiley   +1 more source

Interactions between the bone morphogenetic protein and the planar cell polarity pathways lead to distinctive ethanol‐induced facial defects

Alcohol, Clinical and Experimental Research, Volume 49, Issue 11, Page 2502-2519, November 2025.
Gene–ethanol interactions lie at the heart of FASD. However, the relationship between ethanol‐sensitive genes and the timing and duration of exposure is not well‐understood. Using morphometric and multivariate analyses in zebrafish, vangl2 and gpc4 mutants are ethanol‐sensitive from 10 to 24 h postfertilization, not before or after, leading to facial ...
Raèden Gray, Anna Lloyd, C. Ben Lovely
wiley   +1 more source

An analysis of contractile and protrusive cell behaviors at the superficial surface of the zebrafish neural plate

Developmental Dynamics, Volume 254, Issue 10, Page 1115-1132, October 2025.
Abstract Background The forces underlying convergence and internalization of the teleost neural plate remain unknown. To help understand this morphogenesis, we analyzed collective and individual cell behaviors at the superficial surface of the neural plate as internalization begins to form the neural keel in the hindbrain region of the zebrafish embryo.
Claudio Araya, Raegan Boekemeyer, Francesca Farlie, Lauren Moon, Freshta Darwish, Chris Rookyard, Leanne Allison, Gema Vizcay‐Barrena, Roland Fleck, Millaray Aranda, Masa Tada, Jonathan D. W. Clarke   +11 more
wiley   +1 more source

A thrombomodulin-like gene is crucial to the collective migration of epibolic blastomeres during germ layer formation and organogenesis in zebrafish

Journal of Biomedical Science, 2019
Background Thrombomodulin (TM), an integral membrane protein, has long been known for its anticoagulant activity. Recent studies showed that TM displays multifaceted activities, including the involvement in cell adhesion and collective cell migration in ...
Gang-Hui Lee, Chia-Lin Chang, Wen-Tai Chiu, Tsun-Hsien Hsiao, Po-Yuan Chen, Kuan-Chieh Wang, Cheng-Hsiang Kuo, Bing-Hung Chen, Guey-Yueh Shi, Hua-Lin Wu, Tzu-Fun Fu   +10 more
doaj   +1 more source

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish

Developmental Dynamics, Volume 254, Issue 10, Page 1133-1147, October 2025.
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan, Travis K. Johnson, Zachary Di Pastena, Jarrad N. Fuller, Lee B. Miles, Sebastian Dworkin   +5 more
wiley   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

MedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava, Kalyani Eswar, Sasvat Sayee Ram Ramesh, Akshit Prajapati, Tanvi Sonpipare, Apoorva Basa, Mounika Gubige, Sribala Ponnapalli, Shashidhar Thatikonda, Aravind Kumar Rengan   +9 more
wiley   +1 more source