SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells
Background Basal-like breast cancer (BLBC) is a poor prognosis subgroup of triple-negative carcinomas that still lack specific target therapies and accurate biomarkers for treatment selection.
Ana Sofia Ribeiro +13 more
doaj +1 more source
Multi-state models for survival analysis in cardiology: an alternative to composite endpoints
To the Editor, The main objective of longitudinal studies conducted in cardiology is often time-to-adverse events (AE) to identify possible risk factors or the efficacy of treatment.
Natalia Montoya +3 more
doaj +1 more source
Determining the hazards posed by microplastics (MPs,
Carbery Maddison +4 more
doaj +1 more source
Job insecurity, subjective well-being and job performance: the moderating role of growth mindset
This study aims to analyze the impact of job insecurity on subjective well-being and the impact on job performance, with a growth mindset as the moderating variable.
Epic Anung Anindita Setjo +1 more
doaj +1 more source
'Eastern' Elegy and 'Western' Epic:reading 'orientalism' in Propertius 4 and Virgil's Aeneid [PDF]
This article explores the extent to which the genres of epic and elegy can be considered ‘occidental’ and ‘oriental’ respectively. Such a polarity is apparently constructed in the ‘epic’ and ‘elegiac’ movements of Propertius 4.1, but it is also ...
O'Rourke, Donncha
core +2 more sources
A machine learning approach for single cell interphase cell cycle staging
The cell nucleus is a tightly regulated organelle and its architectural structure is dynamically orchestrated to maintain normal cell function. Indeed, fluctuations in nuclear size and shape are known to occur during the cell cycle and alterations in ...
Hemaxi Narotamo +6 more
doaj +1 more source
EPIC 219388192 b - an inhabitant of the brown dwarf desert in the Ruprecht 147 open cluster [PDF]
We report the discovery of EPIC 219388192 b, a transiting brown dwarf in a 5.3-day orbit around a member star of Ruprecht-147, the oldest nearby open cluster association, which was photometrically monitored by K2 during its Campaign 7.
Albrecht, Simon +34 more
core +6 more sources
A New Era for Educational Assessment
In this article, David Conley focuses on how to assess meaningful learning in ways that promote student achievement while simultaneously meeting system accountability needs.
David Conley
doaj +1 more source
Rethinking planning hierarchy considering climate change as global catastrophe
This article proposes overcoming the distinction between the effects of climate change and the effects linked to classical disaster hazards by considering Climate Change as global catastrophe.
Mattia Bertin +2 more
doaj +1 more source
Fatty acid uptake in Trypanosoma brucei: Host resources and possible mechanisms
Trypanosoma brucei spp. causes African Sleeping Sickness in humans and nagana, a wasting disease, in cattle. As T. brucei goes through its life cycle in its mammalian and insect vector hosts, it is exposed to distinct environments that differ in their ...
Nava Raj Poudyal +3 more
doaj +1 more source

