Results 41 to 50 of about 10,363 (197)

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Epicardial Adipose Tissue Thickness, A Direct Correlation With Age And Gender In Healthy Adults And Coronary Artery Disease Patients

Journal of Bahria University Medical and Dental College, 2021
Objectives: The aim of this study was to measure the Epicardial Adipose Tissue thickness through echocardiography in healthy adults and coronary artery disease patients and to make its association with age and gender.
Sadaf Shaheen, Sahrish Mukhtar, Iffat Raza, Bashir Sheikh   +3 more
doaj   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Metabolic Shifts Induced by Treatment with Statin Influences Circulating Concentrations of the Stress Hormone, Cortisol, but Has Different Effects on Selected Cytokines, Adipokines and Neuropeptides in Lean and Fat Lines of Young Pigs

Metabolites
Background: It was hypothesized that short statin treatment would shift adipose expression, plasma and adipose tissue concentrations of adipokines and cytokines.
Krystyna Pierzchała-Koziec, Colin G. Scanes, Joanna Zubel-Łojek, Mirosław Kucharski   +3 more
doaj   +1 more source

Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies. [PDF]

PLoS ONE, 2013
CONTEXT: Adipokines are linked to the development of cardiovascular dysfunction in type 2 diabetes (DM2). In DM2-patients, circulating levels of omentin-1, an adipokine preferentially expressed in epicardial adipose tissue, are decreased.
Sabrina Greulich, Weena J Y Chen, Bujar Maxhera, Luuk J Rijzewijk, Rutger W van der Meer, Jacqueline T Jonker, Heidi Mueller, Daniella Herzfeld de Wiza, Ralf-Ruediger Floerke, Konstantinos Smiris, Hildo J Lamb, Albert de Roos, Jeroen J Bax, Johannes A Romijn, Jan W A Smit, Payam Akhyari, Artur Lichtenberg, Juergen Eckel, Michaela Diamant, D Margriet Ouwens   +19 more
doaj   +1 more source

Epicardial Adipose Tissue [PDF]

JACC: Cardiovascular Imaging, 2020
Samia Massalha, Jeroen Walpot, Damini Dey, Emel Celiker Guler, Owen Clarkin, Laura Godkin, Indeevari Ratnayake, Pranisha Jayasinghe, Alomgir Hossain, Andrew Crean, Matthew Chan, Craig Butler, Vikas Tandon, Peter Nagele, Pamela K. Woodard, Marko Mrkobrada, Wojciech Szczeklik, Yang Faridah Abdul Aziz, Bruce Biccard, P.J. Devereaux, Tej Sheth, Benjamin J.W. Chow   +21 more
openaire   +2 more sources

Epicardial adipose tissue: an overtly concealed contributor to cardiovascular events in chronic kidney disease patients

Lipids in Health and Disease
Epicardial adipose tissue, a metabolically active visceral fat depot surrounding the heart, is increasingly implicated as a key contributor to cardiovascular disease in patients with chronic kidney disease. This review explores how chronic kidney disease
Liqin Cui, Min Yang
doaj   +1 more source

IMMUNOPHENOTYPE OF MESENCHYMAL STEM CELLS FROM ADIPOSE TISSUE OF PATIENTS WITH CARDIOVASCULAR DISEASES

Байкальский медицинский журнал, 2023
Introduction. Due to a set of unique properties, for example, the ability to differentiate into different types of connective tissue cells, mesenchymal stem cells (MSCs) are attracting more and more attention from researchers.
Evgeniya Gennadievna Uchasova, Julia Alexandrovna Dyleva, Ekaterina Vladimirovna Belik, Vera Gennadievna Matveeva, Sergey Mikhailovich Gusev, Olga Victorovna Gruzdeva   +5 more
doaj   +1 more source

Menopause hormone therapy in women with cardiovascular risk factors or established ischemic heart disease: A joint FIGO and WHF position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto, Martha Gulati, Suvarna S. Khadilkar, Angela H. E. M. Maas, Federica Frezet, Gláucia Maria Moraes de Oliveira, Andrea R. Genazzani, Hema Divakar, Athena Poppas, on behalf of the World Heart Federation (WHF) and the International Federation of Gynecology and Obstetrics (FIGO)   +9 more
wiley   +1 more source

AI-quantified epicardial adipose tissue and prediction of future myocardial infarction in patients with cardiometabolic disease: a post-hoc analysis from the SCOT-HEART trial

Cardiovascular Diabetology
Background Epicardial adipose tissue is gaining increasing interest as a cardiometabolic imaging biomarker, but its exact role in coronary artery disease is not fully understood. This study aimed to investigate the relationship between epicardial adipose
Jolien Geers, Nipun Manral, Caroline Park, Guadalupe Flores Tomasino, Kajetan Grodecki, Joel Lenell, Mikolaj Buchwald, Aryabod Razipour, Jacek Kwiecinski, Hidenari Matsumoto, Mohamed Marwan, Stephan Achenbach, Daniel S. Berman, Marc R. Dweck, David E. Newby, Piotr J. Slomka, Michelle C. Williams, Damini Dey   +17 more
doaj   +1 more source