Results 31 to 40 of about 702,111 (308)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Etiological and Pathological Investigation of Bacterial Pneumonia in Forest Musk Deer (Moschus berezovskii) Using a Novel Multiplex PCR Assay

Veterinary Medicine International
Pneumonia is a major cause of mortality in forest musk deer (M. berezovskii) breeding, leading to significant economic losses. Conventional pathogen detection methods, such as bacterial isolation and culture, are time-consuming and costly.
Cheng Chang, Xiaorui Zhang, Runlai Cao, Qilin Wang, Xiaoxu Wang   +4 more
doaj   +1 more source

THE EPIDEMIC. [PDF]

The Lancet
n ...
openaire   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

African, Native American and European mitochondrials DNAs in Cubans from the Pinar del Rio Province and implications for the recent epidemic neuropathy in Cuba

, 1995
Genetic predisposition, particularly specific mitochondrial DNA (mtDNA) backgrounds, has been proposed as a contributing factor in the expression of an epidemic of bilateral optic neuropathy that has affected residents of Cuba since 1991. To substantiate
NEWMAN NJ, WALLACE DC, BROWN MD, TORRONI, ANTONIO, LOTT MT, THE CUBAN NATIONAL OPERATIVE GROUP ON EPIDEMIC NEUROPATHY   +5 more
core   +1 more source

Opportunities for Refinement of Non-Human Primate Vaccine Studies

Vaccines, 2021
Non-human primates (NHPs) are used extensively in the development of vaccines and therapeutics for human disease. High standards in the design, conduct, and reporting of NHP vaccine studies are crucial for maximizing their scientific value and ...
Mark J. Prescott, Carolyn Clark, William E. Dowling, Amy C. Shurtleff   +3 more
doaj   +1 more source

ON EPIDEMICS. [PDF]

The Lancet
n ...
openaire   +1 more source

Thinking beyond the “epidemic of epidemics”

, 2020
Organisms. Journal of Biological Sciences, Vol 4, No 1 (2020)
openaire   +2 more sources

THE EPIDEMIC OF INFLUENZA. [PDF]

The Lancet, 1890
n ...
Bolton, A. Irwin, Abraham, PhinS
openaire   +2 more sources

The Obesity Epidemic [PDF]

Science, 2004
T here is a growing public health crisis that is global in scope, and it isn't another emerging infectious disease. It concerns being overweight and the adverse health consequences of obesity, which include diabetes, heart disease, and cancer. To sketch the extent of this problem, we begin with the United States, an appropriate starting point because U.
Philip, Abelson, Donald, Kennedy
openaire   +2 more sources