Results 51 to 60 of about 642,453 (316)

Informed decisions about public health and social measures

Health Research Policy and Systems
Evidence, communication, critical thinking and participation are the cornerstones of informed decisions. In this article we discuss each of these in relation to decisions about public health and social measures (PHSM) during the coronavirus disease 2019 (
Andrew D. Oxman, Annlaug Selstø, Arnfinn Helleve, Atle Fretheim, Cathinka Halle Julin, Christine Holst, Christopher James Rose, Heather Munthe-Kaas, Ingeborg Hess Elgersma, Jenny Moberg, Mona Bjørbæk, Petter Elstrøm, Runar Barstad Solberg, Sarah E. Rosenbaum, Signe Flottorp, Tone Bruun, Unni Gopinathan   +16 more
doaj   +1 more source

Contextual Insights for Infectious Pathogen Surveillance Using the Epidemic Intelligence from Open Sources System

Annals of Global Health
Background: Surveillance systems with early warning alert and response (EWAR) objectives often integrate diverse data sources, including laboratory surveillance, community reports, and open-source information for robust public health intelligence.
Farah Kader, Raquel Medialdea Carrera, Carolyn Briody, Julie Fontaine, Yeon Kyeng Lee, Johannes Schnitzler, Philip AbdelMalik   +6 more
doaj   +1 more source

Spatial and temporal variations of malaria epidemic risk in Ethiopia: factors involved and implications.

, 2003
The aim of this study was to describe spatial and temporal variations in malaria epidemic risk in Ethiopia and to examine factors involved in relation to their implications for early warning and interpretation of geographical risk models.
Abeku, Tarekegn Abose, Habbema, JDF, van Oortmarssen, Gerrit J, Borsboom, Gerard, de Vlas, Sake J   +4 more
core   +1 more source

Disease prevention versus data privacy : using landcover maps to inform spatial epidemic models [PDF]

, 2012
The availability of epidemiological data in the early stages of an outbreak of an infectious disease is vital for modelers to make accurate predictions regarding the likely spread of disease and preferred intervention strategies.
Michael J. Tildesley (123224), Tildesley, Michael J., Ryan Sadie J., Tildesley Michael J., Sadie J Ryan, Ryan, Sadie J., Sadie J. Ryan (24547), Michael J Tildesley   +7 more
core   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Why were so few randomized trials of public health and social measures conducted during the COVID-19 pandemic? The Norwegian experience

Trials
Background Few randomized trials of public health and social measures were carried out during the COVID-19 pandemic. We report on the major barriers we faced when we tried to run such trials.
Atle Fretheim, Petter Elstrøm, Cathinka Halle Julin, Unni Gopinathan, Ingeborg Hess Elgersma, Runar Barstad Solberg, Arnfinn Helleve   +6 more
doaj   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Epidemic space [PDF]

, 2005
The aim of this article is to highlight the importance of 'spatiality' in understanding the materialization of risk society and cultivation of risk sensibilities.
van Loon, Joost, Loon, J van
core   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Soldiers and epidemics [PDF]

Clinical Microbiology and Infection, 2012
Epidemics have accompanied wars since antiquity. They have often influenced the outcome of battles and military campaigns, and have occurred among both soldiers and civilians. Favourable conditions for their emergence result from the destruction caused by fighting, the social disorganization and collapse of health systems, the slackening of hygiene and
openaire   +2 more sources