Results 61 to 70 of about 702,111 (308)

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Spatial and temporal variations of malaria epidemic risk in Ethiopia: factors involved and implications.

, 2003
The aim of this study was to describe spatial and temporal variations in malaria epidemic risk in Ethiopia and to examine factors involved in relation to their implications for early warning and interpretation of geographical risk models.
Abeku, Tarekegn Abose, Habbema, JDF, van Oortmarssen, Gerrit J, Borsboom, Gerard, de Vlas, Sake J, de Vlas, Sake, Oortmarssen, Gerrit, Abeku, TA, Habbema, Dik   +8 more
core   +1 more source

Disease prevention versus data privacy : using landcover maps to inform spatial epidemic models [PDF]

, 2012
The availability of epidemiological data in the early stages of an outbreak of an infectious disease is vital for modelers to make accurate predictions regarding the likely spread of disease and preferred intervention strategies.
Michael J. Tildesley (123224), Tildesley, Michael J., Ryan Sadie J., Tildesley Michael J., Sadie J Ryan, Ryan, Sadie J., Sadie J. Ryan (24547), Michael J Tildesley   +7 more
core   +1 more source

Integration of a social network strategy into index testing to increase HIV case finding among Haitian migrants and their descendants in the Dominican Republic

BMC Infectious Diseases
Introduction Increasing effectiveness, efficiency, and reach of HIV case-finding strategies among priority populations is essential for epidemic control.
Caterina Casalini, Molly Goggin-Kehm, Jacob Michel, Roudy Joseph, Ruth Diaz, Gianmarco Martinez, Stevenson Saint-Hilaire, Gercy Mateo, Chris Akolo, Navindra Persaud, Natasha Mack, Katherine Hernandez, Mario Reyes, Ceida Martinez, Leidy Tamarez, Mayra Elizardi, Maria Garcia, Algeni Lorenzo, Johana Molil, Elvis Baez, Rebecca Fertziger, Alejandro Soto   +21 more
doaj   +1 more source

Soldiers and epidemics [PDF]

Clinical Microbiology and Infection, 2012
Epidemics have accompanied wars since antiquity. They have often influenced the outcome of battles and military campaigns, and have occurred among both soldiers and civilians. Favourable conditions for their emergence result from the destruction caused by fighting, the social disorganization and collapse of health systems, the slackening of hygiene and
openaire   +2 more sources

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

Advanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng, Wen‐Kai Wei, Meng‐Yao Wu, Min‐Zheng Cai, Yu‐Fu Wang, Li Zhao, Shuai Meng, Liang‐Fen Yin, Guido Schnabel, Wei‐Xiao Yin, Chao‐Xi Luo   +10 more
wiley   +1 more source

Malaria epidemic early warning and detection in African highlands. [PDF]

, 2004
Malaria epidemics have long been known to recur in the African highlands. Efforts to develop systems of early warning and detection for epidemics are outlined here with special emphasis on the Highland Malaria Project (HIMAL).
de Vlas, SJ, de Vlas, Sake, Cox, J, Ochola, Samuel, Beard, B, Langi, Peter, Cox, Jonathan, Langi, P, Hay, Simon I, Abeku, TA, Beard, Brian, Ochola, S, Hay, SI, Abeku, Tarekegn A, Hay, Simon, de Vlas, Sake J   +15 more
core   +1 more source

Epidemics [PDF]

The Boston Medical and Surgical Journal
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openaire   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

Advanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou, Jianing Jing, Zhuohan Shi, Lei Sun   +3 more
wiley   +1 more source

Rate of inter-herd transmission of classical swine fever virus by different types of contact during the 1997-8 epidemic in The Netherlands [PDF]

, 2002
In this study we quanti®ed the rate at which classical swine fever had been transmitted by several different types of inter-herd contact during the 1997±8 epidemic in The Netherlands. During that epidemic 428 CSFV-infected pig herds were detected, 403 of
Stegeman, J.A., Bouma, A., Jong, M.C.M., de, Elbers, A.R.W.   +3 more
core   +1 more source