Results 71 to 80 of about 642,453 (316)

Is there the potential for an epidemic of variant Creutzfeldt-Jakob disease via blood transfusion in the UK?

, 2007
The discovery of three individuals suspected to have contracted variant Creutzfeldt-Jakob disease (vCJD) through blood transfusions has heightened concerns that a secondary epidemic via human-to-human transmission could occur in the UK. The Department of
Will, Robert G, Ghani, Azra C, Clarke, Paul   +2 more
core   +1 more source

Travelling waves for an epidemic model with non-smooth treatment rates [PDF]

, 2010
This is the post-print version of the final published paper that is available from the link below. Copyright @ 2010 IOP Publishing Ltd and SISSA.We consider a susceptible–infected–removed (SIR) epidemic model with two types of nonlinear treatment rates:
Winter, M, Hussaini, N, N Hussaini, M Winter   +3 more
core   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic [PDF]

, 2004
This paper reviews current understanding of the epidemiology, transmission dynamics and control of the aetiological agent of severe acute respiratory syndrome (SARS).
Hedley, A, Leung, Gabriel M, Ghani, Azra C, Christophe Fraser, Lam, T, Anderson, RM, Ghani, AC, Lam, TH, Azra C. Ghani, Donnelly, C, Leung, GM, Fraser, C, Ferguson, Neil M, Fraser, Christophe, Donnelly, CA, Hedley, AJ, Christl A. Donnelly, Anderson, Roy M, Ferguson, NM, Riley, Steven, Roy M. Anderson, Leung, G, Hedley, Anthony J, Anthony J. Hedley, Ghani, A, Ferguson, N, Anderson, R, Donnelly, Christl A, Steven Riley, Riley, S, Neil M. Ferguson, Gabriel M. Leung, Tai H. Lam   +32 more
core   +2 more sources

Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019

Viruses, 2020
H10, H11 and H12 (H10–H12) subtypes of the avian influenza virus (AIV) are associated with waterfowl. Although these subtypes of AIV are infrequently detected in nature, they can undergo reassortment with other AIV subtypes.
Ling Tang, Wangjun Tang, Le Ming, Jianming Gu, Kai Qian, Xiaofang Li, Tianhou Wang, Guimei He   +7 more
doaj   +1 more source

The Obesity Epidemic

Current Sports Medicine Reports, 2007
Introduction In June 2004, Time Magazine published a special issue titled, “America’s Obesity Crisis.” Exactly 1 year later, Scientific American, in their June 2005 issue, published an article titled, “Obesity: An Overblown Epidemic.” Was the “obesity crisis” resolved within the intervening 12-month period between these publications?
openaire   +3 more sources

Scale-free network of a dengue epidemic

, 2008
In this work we show that the dengue epidemic in the city of Singapore organized itself into a scale-free network of transmission as the 2000-2005 outbreaks progressed.
Massad, E., Chen, M., Stollenwerk, N., Ma, S., Massad, Eduardo, Ma, Stefen, Aguiar, M., Aguiar, Maíra, Chen, Mark, Stollenwerk, Nico, Struchiner, C.J., Struchiner, Cláudio José   +11 more
core   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

The Platform Readiness Dashboard: A Tool for Evaluating Vaccine Platform Suitability for a Rapid Response to Epidemic and Pandemic Threats

Vaccines
Rapid vaccine availability is essential for effective epidemic and pandemic response. Building on the Coalition for Epidemic Preparedness Innovations (CEPI) 100 Days Mission, which aims to have new vaccines ready for initial authorization and ...
Ramin Sabet-Azad, Catherine Hoath, Nicole Bézay, Anna Särnefält   +3 more
doaj   +1 more source

Phylogenetic analysis and pathogenicity assessment of two strains of avian influenza virus subtype H9N2 isolated from migratory birds: High homology of internal genes with human H10N8 virus

Frontiers in Microbiology, 2016
Two human-infecting avian influenza viruses (AIVs), H7N9 and H10N8, have emerged in China. This development further indicates that as an internal gene donor, the H9N2 subtype of AIVs may have an important role in the generation of new viruses with cross ...
Ge eYe, Chai hong liang, Deng guo hua, Lei yong song, Yang guo xing, Chen eGuang, Chen hua lan, Hua yu ping   +7 more
doaj   +1 more source