Results 81 to 90 of about 10,901,260 (303)

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

open access: yesAdvanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang   +6 more
wiley   +1 more source

Retrospective Analysis of Enterovirus Infection Morbidity Rate in the Territory of the Amur Region and Peculiarities of Epidemic Process in the Period of Large-Scale Flood

open access: yesПроблемы особо опасных инфекций, 2014
There has been observed a tendency to increment of enterovirus morbidity rate over the past seven years. Foci of this infection have been formed in the area from time to time, with minor forms of the disease being predominant in clinical findings ...
O. E. Trotsenko   +9 more
doaj   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

open access: yesAdvanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen   +17 more
wiley   +1 more source

Criteria for the integration of epidemic processes of HIV infection and tuberculosis

open access: yesТуберкулез и болезни лёгких, 2019
The objective of the study: to establish criteria for the integration of epidemic processes of HIV infection and tuberculosis. Subjects and methods. The article presents the retrospective analysis of the long-term changes in the main epidemiological ...
S. N. Shugaeva, E. D. Savilov
doaj   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

open access: yesAdvanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao   +6 more
wiley   +1 more source

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

open access: yesAdvanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng   +10 more
wiley   +1 more source

Experimental study on preparedness of disease X with an agent-based framework scenario-driven analysis

open access: yesРадіоелектронні і комп'ютерні системи
Emerging respiratory pathogens continue to impose substantial health and economic burdens worldwide, motivating generic readiness tools that do not rely on pathogen-specific data.
Dmytro Chumachenko
doaj   +1 more source

Baltimore Smallpox Epidemic Collection

open access: yes, 1871
The Baltimore Smallpox Epidemic Collection comprises correspondence and financial records relating to an epidemic between 1871 and 1882. Topics of interest include smallpox vaccinations, measures taken to prevent the spread of the epidemic, including ...
Baltimore Smallpox Epidemic Collection
core  

Measles Epidemic Process in Various Vaccinal Periods [PDF]

open access: yes, 2015
The considerable factual data enabled us for the first time to reveal the peculiarities of measles epidemic process manifestations in different stages of the prophylaxis.
O. V. Tsvirkun   +3 more
core   +1 more source

Voluntary Collective Action to Address Growing Agricultural Challenges in Two Countries: Experimental Insights and Commonalities

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT We conducted two framed field economic experiments with citrus farmers in Florida, United States and soybean farmers in Argentina to investigate their willingness to coordinate pest and weed management efforts. Despite the contrast between these two agricultural contexts, we find striking behavioral commonalities.
Ariel Singerman, Sergio H. Lence
wiley   +1 more source

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