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Practical limitations of epidemiologic methods. [PDF]
Environmental Health Perspectives, 1983 Epidemiologic methods can be categorized into demographic studies of mortality and morbidity and observational studies that are either retrospective or prospective. Some of the limitations of demographic studies are illustrated by a review of one specific mortality study showing possible relationship of nuclear fallout to leukemia. Problems of accuracy
openaire +2 more sources
Growth, current size and the role of the 'reversal paradox' in the foetal origins of adult disease: an illustration using vector geometry [PDF]
, 2006 BACKGROUND Numerous studies have reported inverse associations between birth weight and a range of diseases in later life. These have led to the development of the 'foetal origins of adult disease hypothesis'. However, many such studies have only been
Ellison, G.T.H. +2 more
core +2 more sources
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
, 2016 Recent work has attempted to use whole-genome sequence data from pathogens to reconstruct the transmission trees linking infectors and infectees in outbreaks.
Britton, Tom +3 more
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Application of a geographic information system in the study of spatial aspects of cervical cancer incidence in Belgrade [PDF]
Vojnosanitetski Pregled, 2020 Background/Aim. Cervical cancer is still an important public health problem in Belgrade. The aim of this study was to explore spatial patterns of cervical cancer, provision and accessibility of women’s health service on the primary health care level in ...
Pavlović Nevenka +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Revista de Saúde Pública, 1986 Realizou-se investigação epidemiológica de um surto de gastroenterite em um navio da marinha brasileira. Foram atingidos 184 indivíduos, representando uma taxa de ataque de 72,7%.
Romeo Luiz Baldissera +1 more
doaj +1 more source
Processed Meat and Colorectal Cancer: A Review of Epidemiologic and Experimental Evidence [PDF]
, 2008 Processed meat intake may be involved in the etiology of colorectal cancer, a major cause of death in affluent countries. The epidemiologic studies published to date conclude that the excess risk in the highest category of processed meat-eaters is ...
Corpet, Denis E. +2 more
core +3 more sources
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
AGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022 The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo +3 more
wiley +1 more source