Results 41 to 50 of about 353,577 (280)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Complex Analysis of the Epidemiological Situation of Tuberculosis used as an Additional Tool for Determining the «Risk Areas»on the Siberian Federal District

open access: yesЭпидемиология и вакцинопрофилактика, 2021
Relevance. The article presents an example of using the method of integral assessment of the epidemiological situation of tuberculosis, which is applied to the main statistical criteria as a more accurate approach in assessing the manifestation of the ...
P. A. Khromova   +3 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

EPIDEMIOLOGICAL SITUATION: SPREAD OF INFECTIOUS DISEASES

open access: yes, 2023
This article devoted to open the theme Epidemiological situation: Spread of Infectious Diseases and covers the latest data about main reason of spreading this diseases. Moreover, in the article simple ways of preventing and avoiding infectious diseses were noted.
Hakimova X X, Turayev Sherali
openaire   +1 more source

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

open access: yesArthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Crimean-Congo hemorrhagic fever in the North Caucasian Federal District: overview of the epidemiological situation and improvement of morbidity forecasting method

open access: yesИнфекция и иммунитет, 2022
This article is dedicated to analyzing epidemiological situation of Crimean-Congo hemorrhagic fever in the subjects of the North Caucasian Federal District (from 2005 to 2021) and developing a new approach to improve epidemiological forecasting by using ...
Daria A. Prislegina   +3 more
doaj   +1 more source

Epidemiological situation of Citrus tristeza virus in mainland Portugal [PDF]

open access: yes, 2013
This study was conducted to update the occurrence and molecular variability of Citrus tristeza virus (CTV) isolates recently obtained from surveys in different orchards in mainland Portugal.
Nolasco, Gustavo, Silva, Goncalo
core  

Life history and mating systems select for male biased parasitism mediated through natural selection and ecological feedbacks [PDF]

open access: yes, 2010
Males are often the "sicker" sex with male biased parasitism found in a taxonomically diverse range of species. There is considerable interest in the processes that could underlie the evolution of sex-biased parasitism.
Bacelar, Flora S.   +2 more
core   +5 more sources

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

Tuberculosis in Sumy region: features of the epidemiological situation [PDF]

open access: yes, 2014
Туберкульоз існує з початку історії людства й у сучасних умовах, як і раніше, є дуже актуальною соціальною проблемою. До початку 60-х років минулого сторіччя склалася концепція про туберкульоз як про зникаючу хворобу.
Malysh, Nina Hryhorivna   +3 more
core  

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