Results 51 to 60 of about 548,075 (306)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Enfermedades reumáticas en pacientes con infección por virus de inmunodeficiencia humana, en Guinea-Bissau

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Fundamento: las enfermedades reumáticas en pacientes portadores del virus de la inmunodeficiencia humana son frecuentes, sin embargo, los datos de prevalencia reportados son muy variables.Objetivo: determinar la prevalencia de las enfermedades reumáticas
Leodanis Rodríguez-González, Pedro Rafael Casado-Méndez, Yuneysis Veliz-Guevara, Rafael Salvador Santos-Fonseca, Josefina Cruzata-Bravo   +4 more
doaj  

Descriptive Epidemiology of Orofacial Clefts in Ethiopia [PDF]

, 2017
BACKGROUND: The prevalence of birth defects including orofacial clefts (OFC) in Ethiopia is not known and there is no established birth defects registration system. OBJECTIVES: To investigate the prevalence and incidence of OFC in Ethiopia.
Agbenorku, Butali, Christensen, Conway, Daniel, Das, Eshete, Gundlach, Ireqbulem, Jennifer, Kesande, Khan, Manyama, Martelli-Junior, Mossey, Odhiambo, Orkar, Suleiman, Tolarova   +18 more
core   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Medicina baseada em evidências: instrumento para educação médica permanente entre psiquiatras?

Revista Brasileira de Educação Médica
INTRODUÇÃO: O médico atualizado pode oferecer o melhor cuidado ao paciente e evitar consequências negativas que a defasagem científica pode acarretar. OBJETIVOS: Identificar os meios de atualização utilizados pelos psiquiatras brasileiros; avaliar seus ...
Isabela Yuri Tsuji, Liliana Cavalcanti Zamperin, Selma Rumiko Tsuji, Valéria Garcia Caputo   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Deaths from HIV/AIDS in aged adults in the Federal District

DST, 2020
Introduction: Infection with the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in Brazil experienced a significant increase in the last decade among individuals aged over 60 years.
Ruth da Conceição Costa e Silva Sacco, Raissa Gomes Magalhães, Amanda de Siqueira Cabral, Patrícia Maria Fonseca Escalda   +3 more
doaj  

The risk of misclassifying subjects within principal component based asset index. [PDF]

, 2014
The asset index is often used as a measure of socioeconomic status in empirical research as an explanatory variable or to control confounding. Principal component analysis (PCA) is frequently used to create the asset index.
Abedin, Jaynal, Arnold, Benjamin F, Luby, Stephen P, Nasser, Mohammed, Sharker, Ma Yushuf   +4 more
core   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

EPIDEMIOLOGICAL CHARACTERIZATION OF REPORTED CASES OF MENINGOCOCCAL DISEASE IN THE CITY OF SÃO PAULO, BRAZIL, BETWEEN 2019 AND 2025

Brazilian Journal of Infectious Diseases
Introduction: Meningitis is a communicable infectious disease with a significant disease burden and possible unfavorable outcomes. In this context, the World Health Organization (WHO) and the Pan American Health Organization (PAHO) developed the roadmap “
Nathália Amaro Schmidt, Ana Freitas Ribeiro   +1 more
doaj   +1 more source