Results 61 to 70 of about 227,874 (258)

Descriptive Epidemiology of Human Brucellosis in Oskou County [PDF]

Taṣvīr-i salāmat, 2016
​Background and objectives : Brucellosis is one of the most common Zoonotic infections in the world and Iran. Since this disease is more engaged with workforce and community production, society is imposed by heavy financial losses.
Alireza Zemestani, Nader Faghiri-Beirami, Alireza Hosseinzadeh Fasaghandis, Seyed-Rasoul Hashemi-Aghdam, Adel Ebrahimzadeh   +4 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Snakebites envenoming in the State of Minas Gerais between 2017 and 2022: an epidemiological analysis

Revista Médica de Minas Gerais
Introduction: Snakebites are life-threatening injuries that need quick intensive care. Minas Gerais has one of the highest incidences of Snakebites in Brazil. The main problems related to snakebites are underreporting and treatment delay.
Samir Charride Vilas Boas Késsimos de Salles, Lucas Morais Rodrigues de Oliveira, Anita de Oliveira Silva, Alda Cristina Alves de Azevedo   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Sedentary behavior patterns in non-pregnant and pregnant women

Preventive Medicine Reports, 2017
Sedentary behavior has been associated with adverse health outcomes among pregnant women; however, few studies have characterized sedentary behavior patterns in this population.
Marquis Hawkins, Youngdeok Kim, Kelley Pettee Gabriel, Bonny Jane Rockette-Wagner, Lisa Chasan-Taber   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

O desafio das doenças emergentes e a revalorização da epidemiologia descritiva

Revista de Saúde Pública
Este artigo trata das doenças emergentes e re-emergentes apresentando seu conceito, as principais ocorrências nos últimos 25 anos, e os determinantes dessas ocorrências.
Rita de Cássia Barradas Barata
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Descriptive Epidemiology of Malignant primary osteosarcoma in Tunisia 1980-2016

Asian Pacific Journal of Cancer Care, 2018
Background  Osteosarcoma is a rare malignant tumor of the mesenchymal tissue that accounts for 5% of all malignant tumors in children and teenager.
Fatma Guermazi
doaj   +3 more sources

O desafio das doenças emergentes e a revalorização da epidemiologia descritiva The challenge of emergent disease and the return to descriptive epidemiology

Revista de Saúde Pública, 1997
Este artigo trata das doenças emergentes e re-emergentes apresentando seu conceito, as principais ocorrências nos últimos 25 anos, e os determinantes dessas ocorrências.
Rita de Cássia Barradas Barata
doaj   +1 more source