Results 61 to 70 of about 2,735,226 (296)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Clinical characteristics of patients submitted to surgery in a dental clinic of Southern Santa Catarina

open access: yesO Mundo da Saúde, 2016
This study presents the clinical characteristics and systemic disorders of patients seen at a university clinic of oral surgery. Descriptive study that evaluated 304 records of patients undergoing surgical procedures in a clinic of Oral Surgery from ...
Paula Fernanda de Araujo   +7 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Mortalidade por HIV/Aids no Brasil, 2000-2015: motivos para preocupação?

open access: yesRevista Brasileira de Epidemiologia
RESUMO: Introdução e objetivo: Estudos de mortalidade são fundamentais no monitoramento da epidemia de HIV/Aids. Qualidade e completude dos dados do sistema de informação de mortalidade (SIM) requerem abordagens complementares.
Mark Drew Crosland Guimarães   +3 more
doaj   +1 more source

A descriptive epidemiology of screen-based devices by children and adolescents : a scoping review of 130 surveillance studies since 2000 [PDF]

open access: yes, 2020
Excessive use of screen-based devices can be detrimental for child and adolescent health. While epidemiological reviews have been focusing on traditional screen-based activities (e.g., television, computer use), the availability of newer screen-based ...
Jason A. Bennie   +11 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Is Heart Failure a New Risk Factor for Incident Cancer?

open access: yesFrontiers in Cardiovascular Medicine, 2022
Xueyang Zheng   +3 more
doaj   +1 more source

Descriptive epidemiology of endemic Classical Swine Fever in Cuba

open access: yesSpanish Journal of Agricultural Research, 2018
In Cuba, Classical Swine Fever (CSF) has become an endemic disease since 1993 with several outbreaks each year despite the compulsory vaccination program implemented.
Osvaldo Fonseca   +10 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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