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Epidermal growth factor in blood
Regulatory Peptides, 1986The presence of receptors for epidermal growth factor (EGF) in a wide variety of human tissues and also some tumours indicates an as yet undefined role for EGF and it is therefore necessary to know precise concentrations in blood and other fluids. We have investigated the occurrence of EGF in the circulation and found that in platelet rich plasma, EGF ...
A P, Savage +3 more
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Biochemistry, 1989
Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
M E, Winkler +3 more
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Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
M E, Winkler +3 more
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Cell Biology International, 1995
ABSTRACTEpidermal growth factor (EGF) is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. Egf exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. The EGF receptor is a transmembrane protein tyrosine kinase.
J, Boonstra +5 more
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ABSTRACTEpidermal growth factor (EGF) is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. Egf exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. The EGF receptor is a transmembrane protein tyrosine kinase.
J, Boonstra +5 more
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Epidermal growth factor and transforming growth factor α
Baillière's Clinical Endocrinology and Metabolism, 1991I have attempted here to outline the basic biochemical knowledge that we have now secured on the EGF family of proteins. In the future we will learn much more about the differential role of EGF versus TGF-alpha, about the physiological significance of amphiregulin, the newest member of this family, and about the roles of TGF-alpha and amphiregulin in ...
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Epidermal growth factor and transforming growth factor α
British Medical Bulletin, 1989This review describes the discovery and initial characterization of the epidermal growth factors (EGFs) and transforming growth factors alpha (TGF alpha), the biosynthesis and tissue distribution of these molecules and a brief description of the effects of these molecules in culture and animals.
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Epidermal Growth Factor and Related Growth Factors
International Journal of Dermatology, 1991R A, Yates +3 more
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2013
The epidermal growth factor family includes a number of cytokines inducing the proliferation of epithelial cells. The founding member (EGF) is a small protein containing 53 aminoacids and 3 disulfide bonds inducing the proliferation of cells sharing its receptor (EGFR), a member of the Erb family widely used as target of anti-tumoral biomedicines ...
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The epidermal growth factor family includes a number of cytokines inducing the proliferation of epithelial cells. The founding member (EGF) is a small protein containing 53 aminoacids and 3 disulfide bonds inducing the proliferation of cells sharing its receptor (EGFR), a member of the Erb family widely used as target of anti-tumoral biomedicines ...
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1991
Polypeptide growth factors have attracted considerable interest since the initial description of nerve growth factor (NGF) in 1951 (Levi-Montalcini and Hamburger 1951) and, subsequently, the identification of epidermal growth factor (EGF) in 1962 (Cohen 1962).
R. V. Nardi, A. Guglietta, I. Parikh
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Polypeptide growth factors have attracted considerable interest since the initial description of nerve growth factor (NGF) in 1951 (Levi-Montalcini and Hamburger 1951) and, subsequently, the identification of epidermal growth factor (EGF) in 1962 (Cohen 1962).
R. V. Nardi, A. Guglietta, I. Parikh
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Epidermal growth factor receptors
European Respiratory Journal, 1989D, Veale, G J, Gibson
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