Results 201 to 210 of about 334,289 (309)

Resistance of recurrent epidermal growth factor receptor-altered glioblastoma to anti-epidermal growth factor receptor targeted therapy with osimertinib. [PDF]

Oncologist
Villanacci F, Prost D, Pieri F, Boetto J, Zucchi V, Giusti A, Jacob J, Nichelli L, Cupini S, Allegrini G, Della Porta M, Santonocito OS, Touat M, Di Stefano AL.   +13 more
europepmc   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Risk factors for skin rash among patients with cancer receiving epidermal growth factor receptor inhibitors: a scoping review protocol. [PDF]

BMJ Open
Zhang L, Zhai Y, Wang Y, Wang T, Tan JB, Sun D, Wang Y, Chen Y, Zheng W, Jiang N, Zhou L.   +10 more
europepmc   +1 more source

Epidermal Growth Factor Receptor [PDF]

, 2008
openaire   +1 more source

Dual‐Network Protein Hydrogels Promote Rapid Hemostasis and Immune‐Regulated Scarless Tissue Regeneration

Advanced Science, EarlyView.
A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li, Guorui Zhang, Xinyue Wang, Zhongyu Liu, Ling Yang, Yuhan Bao, Min Wei, Yonglin Chen, Yanfei Ma, Wenbo Sheng, Bo Yu, Bin Li   +11 more
wiley   +1 more source

Pragmatic Clinical Trial Assessing Response to Neoadjuvant Docetaxel and Trastuzumab in Nigerian Women With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer (ARETTA). [PDF]

JCO Glob Oncol
Ntekim A, Popoola A, Sowunmi A, Olasehinde O, Sanni A, Ibraheem A, Zheng Y, Yoshimatsu TF, Dosunmu GT, Omoleye O, Folasire A, Adeniji-Sofoluwe A, Omisore A, Adewumi A, Olajide T, Lawal R, Komolafe A, Omodele F, Ajani M, Michael O, Balogun B, Ale OK, Irurhe N, Folorunso S, Oyekan A, Kotila O, Aniagwu T, Odetunde A, Ilona S, Ajani AO, Oshin A, Onitilo A, Asuzu C, Daramola A, Abdulkareem F, Balogun OO, Karrison T, Babalola P, Huo D, Olopade CO, Obafunwa J, Ojengbede O, Olopade OI.   +42 more
europepmc   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Development and characterization of nucleosomal DNA-based reference materials for the epidermal growth factor receptor gene liquid biopsy. [PDF]

Anal Bioanal Chem
Hong SR, Park J, Lee SS, Kim DY, Cho YJ, Bae YK.   +5 more
europepmc   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source

A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing

Advanced Science, EarlyView.
A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu, Xiujuan Hu, Shengqun Shi, Bowen Li, Zhixing Ge, Yunchen Long, Chaochao Sun, Annan Chen, Bingbing Gao, Lianbo Guo, Condon Lau, Wei Luo, Chwee Teck Lim   +12 more
wiley   +1 more source