Results 191 to 200 of about 503,933 (311)

Advances in Targeted Therapy for Human Epidermal Growth Factor Receptor 2-Low Tumors: From Trastuzumab to Antibody-Drug Conjugates. [PDF]

World J Oncol
Zheng ZN, Ye XH, Shen XB, Li T, Guo J.
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Simulating epidermal growth factor receptor interaction with ligand [PDF]

core   +1 more source

The amphiregulin- epidermal growth factor receptor axis as a therapeutic target in sepsis. [PDF]

Front Immunol
Walsh R, Snow TAC, Martinez AZ, Brealey D, Singer M, Das A, Arulkumaran N, University College London Hospitals Critical Care Research Team.   +7 more
europepmc   +1 more source

Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors

Advanced Science, EarlyView.
A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano, Eleonora Vandini, Eleonora Daini, Antonietta Vilella, Daniela Giuliani, Leonardo Lamanna, Marco Friuli, Christian Demitri, Laura Pecoraro, Amilcare Barca, Tiziano Verri, Cosimino Malitesta, Martina Corsi, Giuseppe Barillaro, Elisabetta Mazzotta   +14 more
wiley   +1 more source

Targeting the epidermal growth factor receptor using IgM antibodies: toward next generation cancer immunotherapy. [PDF]

Front Immunol
Somboon K, Bond PJ, Samsudin F.
europepmc   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Transactivation of epidermal growth factor receptor through platelet-activating factor/receptor in ovarian cancer cells [PDF]

, 2014
Congjian Xu, Mingxing Zhang, Qingqing Cai, Wei Jiang, Xiaoyan Zhang, Yi Yu, Zhiling Zhu   +6 more
core   +1 more source

Epidermal Growth Factor Receptor Mutation in Resectable Lung Cancer: Association With Survival Outcomes. [PDF]

Ann Thorac Surg Short Rep
Bardawil CE, Demanelis K, Suzuki Y, Mazur S, Udoh H, Soloff A, Dhupar R.   +6 more
europepmc   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source