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The Receptor for Epidermal Growth Factor
1987Epidermal growth factor (EGF) is a well-characterized growth factor that was initially isolated from mouse submaxillary glands.(1–3) The low-molecular-weight growth factor (M r 6000) can be isolated as a component of a high-molecular-weight complex with an associated arginine esterase activity. (4,5) EGF has been found in all mammals and, in humans, is
Wendelyn H. Inman, Graham Carpenter
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Epidermal Growth Factor Receptor
1995Abstract The complete nucleotide sequences have been determined for the human EGFR (GenBank accession No X00588), human c-neu (GenBank accession No X03363), human EGFR B3 (HER3, Genbank accession No M29366) and human EGFR B4 (GenBank accession No L07868). Partial sequence information is available for the mouse and chicken EGFRs (Avivi
F Walker, A W Burgess
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Biochemistry, 1989
Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
M E, Winkler +3 more
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Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
M E, Winkler +3 more
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Thyroid, 2001
Thyroid malignancy has been induced by long-term endogenous thyrotropin (TSH) stimulation in experimental animals, leading to local and distant metastasis. It has been postulated that constant and prolonged endogenous TSH stimulation in dyshormonogenetic thyroid tissues could result in thyroid neoplasia.
F, Pedrinola +3 more
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Thyroid malignancy has been induced by long-term endogenous thyrotropin (TSH) stimulation in experimental animals, leading to local and distant metastasis. It has been postulated that constant and prolonged endogenous TSH stimulation in dyshormonogenetic thyroid tissues could result in thyroid neoplasia.
F, Pedrinola +3 more
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Growth Factor Receptors: The Epidermal Growth Factor Receptor as a Model
1990Secreted polypeptide growth factors such as insulin, insulinlike growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and colony-stimulating factor (CSF-1) initiate complex cytoplasmic and nuclear events. These distinct cellular responses can be attributed to the interaction of hormones with their respective ...
K. C. Oberg, A. Brown, G. Carpenter
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Epidermal growth factor receptors
European Respiratory Journal, 1989D, Veale, G J, Gibson
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Epidermal Growth Factor Receptor: Not Just Epidermal
Science Translational Medicine, 2010Inhibition of epidermal growth factor receptor enhances granulocyte colony–stimulating factor–induced mobilization of hematopoietic stem and progenitor cells.
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Gastric carcinoma, epidermol growth factor, and epidermal growth factor receptor
Gastroenterology, 1991E Y, Lee +3 more
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