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Oncology Reports, 1994
We examined the relationship between epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) with clinicopathologic variables and silver-stained nuclear organizer region (Ag-NOR) counts in 93 patients with breast cancer. EGFR expression was significantly associated with axillary lymph node metastases, whereas EGF expression was not ...
M, Noguchi +5 more
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We examined the relationship between epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) with clinicopathologic variables and silver-stained nuclear organizer region (Ag-NOR) counts in 93 patients with breast cancer. EGFR expression was significantly associated with axillary lymph node metastases, whereas EGF expression was not ...
M, Noguchi +5 more
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The Receptor for Epidermal Growth Factor
1987Epidermal growth factor (EGF) is a well-characterized growth factor that was initially isolated from mouse submaxillary glands.(1–3) The low-molecular-weight growth factor (M r 6000) can be isolated as a component of a high-molecular-weight complex with an associated arginine esterase activity. (4,5) EGF has been found in all mammals and, in humans, is
Wendelyn H. Inman, Graham Carpenter
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Epidermal growth factor receptor in adenocarcinoma of the kidney
Urological Research, 1989Epidermal growth factor receptor (EGF-R) was estimated in Hypernephroma by saturation analysis using 125-I EGF as ligand. Tissue levels of this oncogene related protein were increased five-fold (24 to 99 fmol/mg protein) in comparison with the surrounding tumor free tissue (3 to 18 fmoles/mg protein).
Ambs KE +4 more
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Epidermal Growth Factor Receptor as a Target for Chemotherapy
Clinical Colorectal Cancer, 2005The epidermal growth factor receptor (EGFR) is overexpressed in as many as 77% of colorectal cancer (CRC) cases. The EGFR is known to be involved in carcinogenetic processes such as cell proliferation, apoptosis, angiogenesis, cell motility, and metastasis.
Daniel, Vallbohmer, Heinz-Josef, Lenz
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The epidermal growth factor receptor mediates radioresistance
International Journal of Radiation Oncology*Biology*Physics, 2003The epidermal growth factor (EGF) receptor is frequently overexpressed in malignant tumors, and its level is correlated with increased cellular resistance to ionizing radiation. However, no precedent studies have investigated whether expression of EGF receptor would by itself confer on cancer cells resistance to radiation. The current study is aimed to
Ke, Liang +4 more
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Growth Factor Receptors: The Epidermal Growth Factor Receptor as a Model
1990Secreted polypeptide growth factors such as insulin, insulinlike growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and colony-stimulating factor (CSF-1) initiate complex cytoplasmic and nuclear events. These distinct cellular responses can be attributed to the interaction of hormones with their respective ...
K. C. Oberg, A. Brown, G. Carpenter
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Epidermal Growth Factor Receptor: Not Just Epidermal
Science Translational Medicine, 2010Inhibition of epidermal growth factor receptor enhances granulocyte colony–stimulating factor–induced mobilization of hematopoietic stem and progenitor cells.
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Epidermal growth factor receptors
European Respiratory Journal, 1989D, Veale, G J, Gibson
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Gastric carcinoma, epidermol growth factor, and epidermal growth factor receptor
Gastroenterology, 1991E Y, Lee +3 more
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