Results 101 to 110 of about 341,208 (342)

5-hydroxymethylcytosine is a key epigenetic regulator of keratinocyte stem cells during psoriasis pathogenesis [PDF]

, 2019
Epigenetic regulation is now known to play an important role in determining stem cell fate during normal tissue development and disease pathogenesis. In this study, we report loss of 5-hydroxymethylcytosine (5-hmC) mediated by ten-eleven translocation ...
Yuan, Christine Wan-Yin
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Tissue-Specific Functions of fem-2/PP2c Phosphatase and fhod-1/formin During Caenorhabditis elegans Embryonic Morphogenesis

G3: Genes, Genomes, Genetics, 2018
The cytoskeleton is the basic machinery that drives many morphogenetic events. Elongation of the C. elegans embryo from a spheroid into a long, thin larva initially results from actomyosin contractility, mainly in the lateral epidermal seam cells, while ...
Osama Refai, Ryan B. Smit, SarahBeth Votra, David Pruyne, Paul E. Mains   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

A Comparative Neuro-Histological Assessment of Gluteal Skin Thickness and Cutaneous Nociceptor Distribution in Horses and Humans

Animals, 2020
The current project aims to build on knowledge of the nociceptive capability of equine skin to detect superficial acute pain, particularly in comparison to human skin.
Lydia Tong, Melinda Stewart, Ian Johnson, Richard Appleyard, Bethany Wilson, Olivia James, Craig Johnson, Paul McGreevy   +7 more
doaj   +1 more source

A Model for the Development of the Rhizobial and Arbuscular Mycorrhizal Symbioses in Legumes and Its Use to Understand the Roles of Ethylene in the Establishment of these two Symbioses [PDF]

, 2002
We propose a model depicting the development of nodulation and arbuscular mycorrhizae. Both processes are dissected into many steps, using Pisum sativum L. nodulation mutants as a guideline. For nodulation, we distinguish two main developmental programs,
Albrecht C., Albrecht C., Ardourel M., Azcon-Aguilar C., Balaji B., Balestrini R., Barker D.G., Barker S.J., Barker S.J., Barnes D.K., Bauer P., Besmer Y.L., Blancaflor E.B., Blilou I., Bonfante P., Bonfante P., Boogerd F.C., Borisov A.Y., Borisov A.Y., Borisov A.Y., Brewin N.J., Buée M., Caetano-Anolles G., Cao X.F., Cardenas L., Carroll B.J., Catoira R., Catoira R., Cavagnaro T.R., Chang C., Charon C., Ciardi J., Cohn J., Cook D., Cruz A.F., Davidson A.L., Davidson A.L., de Faria S.M., Dehio C., Drennan D.S.H., Duc G., Duc G., Dugassa G.D., Duodu S., Ehrhardt D.W., Ekdahl I., El Ghachtouli N., Engvild K.C., F C Guinel, Fang Y., Fearn J.C., Felle H.H., Felle H.H., Fernández-López M., Fuchs Y., Fukuda H., Gallaud I., Garriock M.L., Geil R.D., Geil R.D., Geitmann A., Genre A., Genre A., Geurts R., Gianinazzi-Pearson V., Giovannetti M., Giovannetti M., Glick B.R., Gollotte A., Goodlass G., Gremaud M.F., Guinel F.C., Guinel F.C., Guinel F.C., Hall M.A., Hamilton A.J., Harrison M.J., Heidstra R., Hirayama T., Hirsch A.M., Hirsch A.M., Hirsch A.M., Hirsch A.M., Hirsch A.M., Hua J., Hunter W.J., Ishii T., John P., Johnson P.R., Joshi P.A., Kneen B.E., Kneen B.E., Kneen B.E., Kobayashi I., Kolchinsky A., Kombrink E., Le Gal M.F., Lee K.H., Lee K.H., Lee K.H., Lhuissier F.G.P., Ligero F., Ligero F., Lorteau M.-A., Luschnig C., Lynch J., Markwei C.M., Markwei C.M., Marsh J.F., Martínez-Abarca F., Mateos P.F., Mathesius U., Mathesius U., Matsubara Y., Matthysse A.G., Mattoo A.K., McArthur D.A.J., Morandi D., Mort A.J., Morzhina E.V., Mylona P., Nadian H., Nagahashi G., Niebel A., Nukui N., Oldroyd G.E.D., Osborne D.J., Park S.J., Parniske M., Paruvangada V.G., Pawlowski K., Peters N.K., Peterson R.L., Postma J.G., Provorov N.A., R D Geil, Rae A.L., Reddy A.S.N., Resendes C.M., Roberts I.N., Sagan M., Sagan M., Salzer P., Santos R., Santos R., Schauser L., Schmidt J.S., Schneider A., Schultze M., Sen D., Senoo K., Smalle J., Smith F.A., Solano R., Sprent J.I., Sprent J.I., Steen D.A., Stougaard J., Stougaard J., Subba-Rao N.S., Suganuma N., Sugimoto K., Szczyglowski K., Theologis A., Timmers A.C.J., Timmers A.C.J., Todaka I., Tsyganov V.E., Tsyganov V.E., Tsyganov V.E., van Rhijn P., van Spronsen P.C., van Spronsen P.C., van Spronsen P.C., van Workum W.A.T., Vasse J., Vasse J., Vega-Hernandez M.C., Vernoud V., Vierheilig H., Vogel J.P., Voroshilova V.A., Wais R.J., Walker S.A., Wegel E., Wisniewski J.-P., Yang W.-C., Yang W.-C., Yasuta T., Young J.P.W., Yuhashi K.-I., Zaat S.A.J., Zhou L.   +192 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Wearable Alcohol Monitoring Device for the Data-Driven Transcutaneous Alcohol Diffusion Model

Sensors
Wearable alcohol monitoring devices demand noninvasive, real-time measurement of blood alcohol content (BAC) reliably and continuously. A few commercial devices are available to determine BAC noninvasively by detecting transcutaneous diffused alcohol ...
Ahmed Hasnain Jalal, Sepehr Arbabi, Mohammad A. Ahad, Fahmida Alam, Md Ashfaq Ahmed   +4 more
doaj   +1 more source

Epithelial expression of the hormone leptin by bovine skin

European Journal of Histochemistry, 2019
Leptin (Lep) stimulates keratinocytes to proliferate, intervenes in the wound healing and participates to hair follicle morphogenesis and cycle. While it is secreted by skin structures including epidermis and hair follicles, intradermal adipose tissue ...
Francesca Mercati, Cecilia Dall'Aglio, Ludovica Timperi, Paola Scocco, Elena De Felice, Margherita Maranesi   +5 more
doaj   +1 more source

Characterisation of Embryonic Dermal Precursor Cells [PDF]

, 2018
Skin is an attractive organ for the acquisition of stem cells due to its accessibility, size and potential for autologous transplants. Research into skin development has implications for the isolation of stem cell populations, for example skin-derived ...
BLINCKO, SARAH
core