Results 31 to 40 of about 9,520 (184)

Full-thickness Skin Grafts for Hand Contractures in an Adult Patient with Junctional Epidermolysis Bullosa: A Case Report

Journal of Plastic and Reconstructive Surgery, 2023
Epidermolysis bullosa is a group of inherited skin fragility disorders with blister formation in the basement membrane zone. Chronic scarring after repeated blistering of the hands causes narrowing of the first web, flexion contractures of the digits ...
Sayaka Nakamura, Susumu Saito, Yoshihiro Ishida, Yo Kaku, Ken Natsuga, Naoki Morimoto   +5 more
doaj  

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Validation of the Investigator's Global Assessment Scale for Epidermolysis Bullosa Simplex

JEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a lack validated outcome measures to assess wound severity in epidermolysis bullosa simplex (EBS). Objectives To assess the reliability and validity of the Investigator's Global Assessment (IGA) scale and a newly developed palms/soles subscale through in‐clinic scoring and review of patient‐submitted photographs.
Pirunthan Pathmarajah, Shufeng Li, Maya B. Mathur, Joyce M. C. Teng, M. Peter Marinkovich, Austin N. Johnson, Shehla Admani, Edward Eid, Joanna Tu, Dominique C. Mitchell, Lila Perrone, Ricardo Villanueva Gaona, Jean Y. Tang, Albert S. Chiou   +13 more
wiley   +1 more source

Rat model for dominant dystrophic epidermolysis bullosa: glycine substitution reduces collagen VII stability and shows gene-dosage effect. [PDF]

PLoS ONE, 2013
Dystrophic epidermolysis bullosa, a severely disabling hereditary skin fragility disorder, is caused by mutations in the gene coding for collagen VII, a specialized adhesion component of the dermal-epidermal junction zone.
Alexander Nyström, Jens Buttgereit, Michael Bader, Tatiana Shmidt, Cemil Ozcelik, Ingrid Hausser, Leena Bruckner-Tuderman, Johannes S Kern   +7 more
doaj   +1 more source

The Use of Blue Light as an Antimicrobial Treatment Against Staphylococcus aureus: A Systematic Review

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Staphylococcus aureus (S. aureus) is a major cause of skin, wound, and device‐related infections. Blue light (405–470 nm), shows promise for treating this organism. However, the translatability, dosing parameters, safety, and effectiveness remain unclear, and no systematic review currently exists.
Alexander Idrogo‐Lam, Kofi Owusu‐Ansah, Eric Cotter, Lisa Cotter   +3 more
wiley   +1 more source

Genomics and epigenomics of tissue repair: Implications for personalized medicine

Precision Medical Sciences, EarlyView.
Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi, Chandrashekar Thalluri, Sarad Pawar Naik Bukke, Piyali Dey, Mallikarjun Vasam, Ananda Kumar Chettupalli, Swetha Kumari Koduru, Gali Avinash Kumar   +7 more
wiley   +1 more source

Reproductive alternatives for patients with dystrophic epidermolysis bullosa

Einstein (São Paulo)
Epidermolysis bullosa describes a group of skin conditions caused by mutations in genes encoding proteins related to dermal-epidermal adhesion. In the United States, 50 cases of epidermolysis bullosa per 1 million live births are estimated, 92% of which ...
Denise Maria Christofolini, José Ricardo Magliocco Ceroni, Giovanna Guimarães Soares, Gustavo Bertollini Lamy, Ana Carolina Nemeth Calvo, Tamara Alba dos Santos, Bianca Del Bel Sonoda, Bianca Bianco, Caio Parente Barbosa   +8 more
doaj   +1 more source

A Systematic Review of Topical and Systemic Gentamicin for Wound Healing in Patients With Junctional and Dystrophic Epidermolysis Bullosa

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Epidermolysis bullosa (EB) is an inherited mechanobullous genodermatosis caused by a mutation in genes encoding proteins integral to skin integrity. Premature termination codon readthrough therapies, such as gentamicin, have promise in facilitating full‐length protein expression in patients with EB.
Kelvin Truong, Joseph Joseph, Deborah Poh, Orli Wargon, Artiene Tatian   +4 more
wiley   +1 more source

Epidermolysis bullosa: an exceptional cause of dysphagia

PAMJ Clinical Medicine, 2019
Epidermolysis bullosa is a genetically transmitted disorder characterized by skin blistering and scarring after minor traumatism, involves also internal organs that are lined with squamous epithelium.
Fouad Nejjari, Tarik Adioui, Hassan Doulhoussne, Iias Benchafii, Sarah Jamal, Ayoub Aoumari, Mouna Tamzaourte, Aziz Aourarh   +7 more
doaj   +1 more source

Prevalence and molecular genetic features of epidermolysis bullosa in Krasnodar Krai

Кубанский научный медицинский вестник, 2020
Background. Epidermolysis bullosa defi nes a clinically and genetically heterogeneous group of severe orphan disorders manifested with a congenital propensity for bullae (blisters) propagation on skin and mucous membranes of oesophagus, intestine ...
I. I. Pavlyuchenko, L. R. Gusaruk, E. E. Tekutskaya, I. T. Rubtsova   +3 more
doaj   +1 more source