Results 11 to 20 of about 9,520 (184)

SINE Insertion in LAMA3 in Dogs With Junctional Epidermolysis Bullosa. [PDF]

Anim Genet
ABSTRACT Junctional epidermolysis bullosa (JEB) is a hereditary skin disorder caused by defects in proteins responsible for dermal‐epidermal adhesion. We investigated the genetic cause of JEB in three related mixed‐breed puppies presenting with congenital skin blistering and ulceration. Whole‐genome sequencing of one affected dog followed by comparison
Kiener S, Kaufmann R, Brenner O, Jagannathan V, Leeb T.   +4 more
europepmc   +2 more sources

Trophoblast Extracellular Vesicles Rewire Immunity: A Symptom-Relief Avenue for Recessive Dystrophic Epidermolysis Bullosa. [PDF]

J Extracell Vesicles
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Hirt N, Manchon E, Wu M, Buanec HL, Bataille P, Bourrat E, Bouaziz JD, Jabrane-Ferrat N, Al-Daccak R.   +8 more
europepmc   +2 more sources

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Epidermolysis bullosa acquisita

Anais Brasileiros de Dermatologia, 2022
Epidermolysis bullosa acquisita is a rare autoimmune disease, characterized by the synthesis of anti-collagen VII autoantibodies, the main component of hemidesmosome anchoring fibrils. The antigen-antibody binding elicits a complex inflammatory response, which culminates in the loss of dermo-epidermal adhesion of the skin and/or mucous membranes.
Denise Miyamoto, Juliana Olivieri Gordilho, Claudia Giuli Santi, Adriana Maria Porro   +3 more
openaire   +5 more sources

Deficient skin proteins rescue of expression in patients with epidermolysis bullosa: efficacy of gentamicin [PDF]

Vestnik Dermatologii i Venerologii
Epidermolysis bullosa is a group of rare hereditary skin diseases based on mutations in the genes of structural proteins of the epidermis and the dermal-epidermal junction.
Olga G. Artamonova, Arfenya E. Karamova, Alexey A. Kubanov, Vadim V. Chikin, Ekaterina S. Monchakovskaya   +4 more
doaj   +1 more source

Dermatofibrosarcoma protuberans in a young patient with epidermolysis bullosa: a case report

BMC Surgery, 2021
Background Epidermolysis bullosa is a group of rare inherited skin diseases characterized by blister formation following mechanical skin trauma. Epidermolysis bullosa is associated with increased skin cancer rates, predominantly squamous cell carcinomas,
B. Bonaventura, D. Kraus, G. B. Stark, H. Fuellgraf, J. Kiefer   +4 more
doaj   +1 more source

Dystrophic Epidermolysis Bullosa

Journal of Nepal Medical Association, 2018
Epidermolysis bullosa is a rare inherited blistering disease with an incidence of 8-10 per million live births. Dystrophic epidermolysis bullosa is a type of epidermolysis bullosa caused by mutation in type VII collagen, COL7A1.
Randhir Sagar Yadav, Amar Jayswal, Shumneva Shrestha, Sanjay Kumar Gupta, Upama Paudel   +4 more
doaj   +1 more source

Acute renal failure in a patient with epidermolysis bullosa acquisita [PDF]

Anais Brasileiros de Dermatologia, 2017
: Epidermolysis bullosa acquisita is a severe autoimmune subepidermal bullous disease. In this report, we described for the first time a patient with epidermolysis bullosa acquisita who developed acute renal failure.
Guowei Zhao, Qing Yang, Furen Zhang
doaj   +1 more source

Endothelial dysfunction in patients with various forms of congenital epidermolysis bullosa

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
Introduction. The endothelial system is an important component of vascular-platelet hemostasis, capable of actively responding to mechanical and inflammatory agents.
V. I. Kornev, O. N. Startseva, A. S. Pleshkov, M. V. Nikiforov   +3 more
doaj   +1 more source

Junctional Epidermolysis Bullosa in a 30-day-old Infant: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2023
Epidermolysis bullosa is a group of hereditary mechanobullous disorders which are associated with appearance of bullae secondary to physical stress like heat or mechanical trauma or sometimes without any trigger.
Pratima Bisen, Sumeet Baheti, Amol Nagre, Chitra Nayak, Poonam Wade   +4 more
doaj   +1 more source