Results 71 to 80 of about 23,997 (201)

EndoS reduces the pathogenicity of anti-mCOL7 IgG through reduced binding of immune complexes to neutrophils. [PDF]

PLoS ONE, 2014
Endo-β-N-acetylglucosaminidase (EndoS) has been shown to act as a potent pathogen-derived immunomodulatory molecule in autoimmune diseases. Here we investigated how EndoS treatment reduces the pathogenicity of rabbit anti-mCOL7 IgG using different ...
Xinhua Yu, Junfeng Zheng, Mattias Collin, Enno Schmidt, Detlef Zillikens, Frank Petersen   +5 more
doaj   +1 more source

Familial epidermolysis bullosa acquisita

Dermatology Online Journal, 2008
Epidermolysis bullosa acquisita (EBA) is an acquired blistering skin disorder caused by IgG autoantibodies directed against type VII collagen. In contrast to the genetic forms of epidermolysis bullosa, EBA is usually an acquired, sporadic disease. In this report, we describe a family with two cases of EBA in an uncle-nephew pair, and a third family ...
Noe, Megan H, Chen, Mei, Woodley, David T, Fairley, Janet A   +3 more
openaire   +4 more sources

Lip swelling and constipation: Pretest probability of cutaneous signs for crohn's disease in the absence of typical gastrointestinal symptoms

Clinical Dermatology Review, 2020
We describe a female child in the first decade patient admitted to a children's hospital for lip swelling and constipation who was ultimately diagnosed with Crohn's disease.
Maggie L Chow, Minnelly Luu
doaj   +1 more source

Epidermolysis Bullosa Acquisita Antigen, a New Major Component of Cutaneous Basement Membrane, Is a Glycoprotein with Collagenous Domains [PDF]

, 1986
The epidermolysis bullosa acquisita antigen is a major constituent of the basement membrane zone beneath stratified squamous epithelium. The antigen which is recognized in extracts of skin basement membrane by Western blot analysis with polyclonal or ...
O'Keefe, Edward, Woodley, David, Reese, Melinda, Briggaman, Robert, Gammon, W. Ray, Mechanic, Gerald   +5 more
core   +3 more sources

Epidermolysis Bullosa Acquisita Occuring In A Patient With Systemic Lupus Erythematosus

Saintika Medika, 2019
Epidermolysis Bullosa Acquisita (EBA) is a rare, chronic autoimmune subepidermal bullous disease and has been noted to be associated with systemic lupus erythematosus (SLE). The incidence of EBA and SLE in one patient within the period of 1980-1990 found
Lita setyowatie, Yustian Devika Rahmawati, Arif Widiatmoko, Diah Prabawati Retnani   +3 more
doaj   +1 more source

Bullous Pemphigoid and Other Pemphigoid Dermatoses

Medicina, 2021
The pemphigoid family of dermatoses is characterized by autoimmune subepidermal blistering. The classic paradigm for pemphigoid, and the most common member, is bullous pemphigoid.
Valeryia Pratasava, Vikram N. Sahni, Aishwarya Suresh, Simo Huang, Abhirup Are, Sylvia Hsu, Kiran Motaparthi   +6 more
doaj   +1 more source

Multiple modes of action mediate the therapeutic effect of IVIg in experimental epidermolysis bullosa acquisita.

Journal of Investigative Dermatology, 2021
Substitution of IgG in antibody deficiency or application of high-dose intravenous IgG (IVIg) in patients with autoimmunity are well-established treatments.
E. Pipi, A. Kasprick, H. Iwata, S. Goletz, J. Hundt, H. Sadeghi, L. Schmidt-Jiménez, E. Schmidt, Jonathan Sjögren, D. Zillikens, R. Ludwig, M. Collin, K. Bieber   +12 more
semanticscholar   +1 more source

Functional Heterogeneity of Immune Complexes in Epidermolysis Bullosa Acquisita [PDF]

, 1987
Epidermolysis bullosa acquisita is an inflammatory subepidermal bullous disease characterized by circulating and tissue-bound complement-binding anti-basement membrane zone autoantibodies to type VII procollagen.
Briggaman, Robert A., Gammon, W. Ray, W. Ray Gammon, Robert A. Briggaman   +3 more
core   +1 more source

Distinguishing Epidermolysis Bullosa Acquisita From Bullous Pemphigoid Without Direct Immunofluorescence

, 2017
Background: It has been postulated that periodic acid–Schiff staining of basement membrane can predict direct immunofluorescence patterns seen in epidermolysis bullosa acquisita and bullous pemphigoid.
Kerry M. Gardner, Richard I. Crawford
core   +1 more source

Childhood epidermolysis bullosa acquisita: Confirmation of diagnosis by skin deficient in Type VII Collagen, enzyme-linked immunosorbent assay, and immunoblotting

Indian Journal of Dermatology, 2016
Epidermolysis bullosa acquisita (EBA) is an acquired subepidermal bullous disorder characterized by autoantibodies against Type VII collagen. It usually affects adults; childhood EBA is rare. We describe a 10-year-old girl presenting with recurrent tense
Nupur Goyal, Raghavendra Rao, C Balachandran, Sathish Pai, Balbir S Bhogal, Enno Schmidt, Detlef Zillikens   +6 more
doaj   +1 more source