Results 91 to 100 of about 23,997 (201)

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1137-1161, July 2026.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda   +31 more
wiley   +1 more source

Bruton tyrosine kinase (Btk) in neutrophils is indispensable for initiating and maintaining skin inflammation in a model of pemphigoid diseases

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2446-2463, May 2026.
Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich   +7 more
wiley   +1 more source

A Multifaceted Holistic Review of the Literature on Scar Dermatoses

open access: yesInternational Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Many cutaneous diseases originate or manifest in scars. Scars are areas of compromised skin, which renders them a vulnerable cutaneous district for diseases to develop. The pathophysiology explaining why some dermatoses grow in scars is not yet thoroughly explored. The present study reviews the present literature on scar dermatoses.
Dana Maria Khoury   +5 more
wiley   +1 more source

A rare occurrence of epidermolysis bullosa acquisita in a patient with retroviral disease

open access: yes, 2017
Epidermolysis bullosa acquisita is a chronic subepidermal blistering disease associated with autoimmunity to type-VII collagen within anchoring fibrils located at the dermo-epidermal junction. This entity is rarely reported from India.
Tambe Swagata   +3 more
core   +1 more source

Autoimmune blistering diseases in females: a review

open access: yesInternational Journal of Women's Dermatology, 2015
The autoimmune blistering diseases (AIBDs) are a group of heterogeneous skin diseases with autoantibodies directed against structural proteins in the skin.
Cathy Y. Zhao, MBBS, MMed   +1 more
doaj   +1 more source

Epidermolysis bullosa: how social support affects quality of life

open access: yes, 2018
Measuring quality of life has become an increasingly important method of evaluating the effect of health and social care interventions. The rare genetic condition epidermolysis bullosa is known to have a deep social impact on people’s quality of life ...
Butterworth, Sondra   +3 more
core   +2 more sources

Epidermolysis Bullosa Acquisita

open access: yesVestnik dermatologii i venerologii, 2015
The article describes present-day information on the pathogenesis, clinical picture, treatment and differential diagnostics of epidermolysis bullosa acquisita, an autoimmune skin disease caused by the production of anti-Type VII collagen autoantibodies and manifested mainly by subepidermal blisters and erosions.
Catherine Prost-Squarcioni   +1 more
openaire   +4 more sources

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

open access: yesJournal of Oral Pathology &Medicine, Volume 55, Issue 4, Page 391-418, April 2026.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini   +9 more
wiley   +1 more source

A Case of Bullous Skin Disease Presenting with Odynophagia: A Diagnostic Challenge

open access: yesCase Reports in Dermatological Medicine, 2016
We report a case of Epidermolysis Bullosa Acquisita (EBA) that presented as a diagnostic challenge. A 60-year-old Qatari lady presented with odynophagia, oral ulceration, and weight loss.
G. Kravvas, D. Veitch, C. M. Perrett
doaj   +1 more source

Hemidesmosome Mutations Contribute to the Onset and Severity of Acquired Autoimmune Bullous Diseases

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This study examined hemidesmosome assembly‐related genes in pemphigoid diseases, revealing variants linked to disease onset and severity. Functional analyses, including Caenorhabditis elegans models, Ker‐CT transcriptomics, human proteomics, etc., demonstrated that ITGA6 mutations destabilize hemidesmosomes, disrupt dermal–epidermal adhesion, and ...
Shan Cao   +19 more
wiley   +1 more source

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