Results 31 to 40 of about 34,244 (203)

Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors

open access: yesAdvanced Science, EarlyView.
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos   +6 more
wiley   +1 more source

Busulfan administration replicated the characteristics of the epididymal initial segment observed in mice lacking testis-epididymis lumicrine signaling

open access: yesThe Journal of Reproduction and Development
The physiological functions of the mammalian epididymis are typically regulated by the testes. In addition to sex steroids secreted by testicular Leydig cells, which act on the epididymis in an endocrine manner, there is a non-sex-steroidal signaling ...
Daiji KIYOZUMI
doaj   +1 more source

Canine and Feline Epididymal Semen—A Plentiful Source of Gametes

open access: yesAnimals, 2021
Canine and feline epididymal semen provide an additional source of gametes to preserve the genetics of valuable breeding dogs and tomcats, especially for those that fail to ejaculate, need castration as a therapy or die unexpectedly.
Hiba Ali Hassan   +5 more
doaj   +1 more source

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma   +17 more
wiley   +1 more source

Epididymal Leiomyoadenomatoid Tumour: A Rare Case Report and Literature Review

open access: yesJournal of Urological Surgery, 2021
Adenomatoid tumours are benign neoplasms of mesothelial origin that most often occur in the epididymis in men and the uterus or fallopian tubes in women.
Fatih Yılmaz   +4 more
doaj   +1 more source

Biomarker‐Agnostic Detection of Ovarian Cancer from Blood Plasma Using a Machine Learning‐Driven Electronic Nose

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces a biomarker‐agnostic diagnostic strategy for ovarian cancer, utilizing a machine learning‐enhanced electronic nose to analyze volatile organic compound signatures from blood plasma. By overcoming the dependence on specific biomarkers, this approach enables accurate detection, staging, and cancer type differentiation, offering a ...
Ivan Shtepliuk   +4 more
wiley   +1 more source

The significance of single-cell transcriptome analysis in epididymis research

open access: yesFrontiers in Cell and Developmental Biology
As a crucial component of the male reproductive system, the epididymis plays multiple roles, including sperm storage and secretion of nutritive fluids for sperm development and maturation.
Meng-Meng Liu   +4 more
doaj   +1 more source

Morphological changes of cauda epididymis, sperm infiltration into cauda epididymis, sperm storage and sperm disappearance of cauda epididymis in Rhinolophus ferrumequinum korai (Chiroptera: Rhinolophidae)

open access: yesThe European Zoological Journal, 2018
In this study to investigate the male reproductive cycle of Rhinolophus ferrumequinum korai, we focused on monthly morphological changes of cauda epididymis, sperm infiltration into cauda epididymis, sperm storage and sperm destruction.
Jung-Hun Lee
doaj   +1 more source

Primary extranodal marginal zone lymphoma - Epididymis

open access: yesIndian Journal of Urology, 2011
An elderly male presented with painful swelling in the right side of scrotum. He was treated with antibiotics for epididymoorchitis without any response. Ultrasound examination revealed a hypoechoic vascular mass in the tail of the epididymis.
Shanmugasundaram Rajaian   +3 more
doaj   +1 more source

A contribution to the anatomy of two rare cetacean species: The hourglass dolphin (Cephalorhynchus cruciger) and the spectacled porpoise (Phocoena dioptrica)

open access: yesThe Anatomical Record, EarlyView.
Abstract The anatomical description of the hourglass dolphin (Cephalorhynchus cruciger) and the spectacled porpoise (Phocoena dioptrica) remains largely unexplored, due to limited specimen availability and preservation challenges. This study employed digital imaging techniques, conventional histology, and computed tomography to provide visualization of
Jean‐Marie Graïc   +26 more
wiley   +1 more source

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