Results 151 to 160 of about 45,935 (222)

Epigallocatechin Gallate Modulates the Cellular Response to Doxorubicin in HeLa Cervical Cancer Cells. [PDF]

Biomolecules
Ayağ ME, Tuncer MC, Öztürk Ş.
europepmc   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

Phytotherapy Research, Volume 40, Issue 10, Page 5973-5987, October 2026.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam, Abdur Rauf, F. M. Shourav, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Kamala Badalova, Marcello Iriti   +7 more
wiley   +1 more source

Sensory signaling mediates the systemic metabolic and neurological effects of epigallocatechin gallate. [PDF]

Front Nutr
Yoshida Y, Iida N, Iwasa K, Saito A, Aso K, Fujii Y, Modafferi S, Calabrese V, Ohmoto M, Abe K, Osakabe N.   +10 more
europepmc   +1 more source

Ceratonia siliqua: Phytochemistry, Bioactivity, and Its Emerging Role as a Sustainable Food and Industrial Resource

Journal of Food Science, Volume 91, Issue 10, October 2026.
ABSTRACT Ceratonia siliqua L. (C. siliqua), commonly known as the carob tree, is an evergreen species of the Fabaceae family native to the Mediterranean basin and increasingly cultivated worldwide. Traditionally valued as animal feed and a natural sweetener, it has recently gained recognition as a multifunctional plant resource with nutritional ...
Anis Ben Hsouna, Ravendra Kumar, Manjul Gondwal, Shivangi Chamoli, Bhanu Pratap Singh Gautam, Simranpreet Kaur, Rakesh Kumar Verma, Piyush Kumar, Monika Michalak, Boutheina Ben Akacha, Wirginia Kukula‐Koch, Wojciech Koch, Faical Brini, Wissem Mnif, Rania Ben Saad, Stefania Garzoli, Miroslava Kačániová   +16 more
wiley   +1 more source

Oxidative Characteristics of Turkey Hemoglobin A Containing Covalently Bound Epigallocatechin Gallate. [PDF]

J Agric Food Chem
Yin J, Zhang W, Tatiyaborworntham N, Bingman CA, Richards MP.   +4 more
europepmc   +1 more source

Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan

Aging Cell, Volume 25, Issue 10, October 2026.
Phenotypic screening and SAR‐guided drug design identified two flavonoid‐derived senolytics, SR29384 and SR31133, which selectively killed different types of senescent cells more efficiently and with greater selectivity than fisetin in culture. In aged and progeroid mice, these fisetin analogs reduced tissue senescence and improved physical function ...
Lei Justan Zhang, Rahagir Salekeen, Carolina Soto‐Palma, Qiuming Wu, Yuanjun He, Osama Elsallabi, Bilel Bdiri, Brian Hughes, Allancer Nunes, Wandi Xu, Borui Zhang, Abdalla Mohamed, Sara J. McGowan, Luise Angelini, Ryan O'Kelly, Theodore M. Kamenecka, Laura J. Niedernhofer, Paul D. Robbins   +17 more
wiley   +1 more source

Epigallocatechin gallate is associated with PDGFRB downregulation and altered PI3K-AKT signaling in gastric cancer. [PDF]

Transl Cancer Res
Zhao Y, Li Y, Zheng H.
europepmc   +1 more source

Combining the chemotherapeutic effects of epigallocatechin 3-gallate with siRNA-mediated p53 knock-down results in synergic pro-apoptotic effects

, 2012
Ioana Berindan-Neagoe,1,2 Cornelia Braicu,1 Alexandru Irimie3,41Department of Functional Genomics and Experimental Pathology, Cancer Institute, “Ion Chiricuta”, Cluj-Napoca, Romania; 2Department of Immunology, University of Medicine ...
Irimie A, Berindan-Neagoe I, Braicu C
core  

To Treat or Not to Treat: Navigating Early‐Stage CLL in the Era of Targeted Therapy

European Journal of Haematology, Volume 117, Issue 4, Page 750-766, October 2026.
ABSTRACT Chronic lymphocytic leukemia (CLL) is most frequently diagnosed at early, asymptomatic stages (Rai 0/Binet A), in which a watch‐and‐wait strategy remains the standard of care, based on historical trials demonstrating no overall survival benefit from early treatment.
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Giovanna Cutrona, Antonella Bruzzese, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Nicola Amodio, Franco Fais, Antonino Neri, Manlio Ferrarini, Valter Gattei, Fortunato Morabito, Massimo Gentile   +16 more
wiley   +1 more source

Plant‐Derived Senolytic Ingredient, Camellia sinensis Root Extract, Ameliorates Skin Aging‐Associated Phenotypes

Experimental Dermatology, Volume 35, Issue 10, October 2026.
Camellia sinensis root extract (SENOMUNE) preferentially reduced senescent dermal fibroblast viability and decreased SASP‐associated factor expression and secretion. Its effects were associated with features consistent with LMP/cathepsin/AIF‐associated caspase‐independent cell death.
Sunyoung Park, Siyoung Cho, Daejin Min, Hyunjung Choi, Kyeonghwan Hwang, In Sup Kil, Won‐Seok Park, Hyoung‐June Kim   +7 more
wiley   +1 more source