Results 61 to 70 of about 43,533 (191)

EEG functional connectivity as a Riemannian mediator: An application to malnutrition and cognition

open access: yesHuman Brain Mapping, Volume 45, Issue 7, May 2024.
This study introduces a novel mediation analysis approach using EEG cross‐spectra to investigate whether malnourishment affects children's cognitive performance. The results indicate that brain function across delta, theta, alpha, and beta band frequencies mediates the impact of malnourishment on cognitive performance in specific brain regions ...
Carlos Lopez Naranjo   +16 more
wiley   +1 more source

Aristotle on Epigenesis [PDF]

open access: yes, 2018
It has become somewhat of a platitude to call Aristotle the first epigenesist insofar as he thought form and structure emerged gradually from an unorganized, amorphous embryo. But modern biology now recognizes two senses of “epigenesis”.
Henry, Devin
core  

Differential expression of conserved germ line markers and delayed segregation of male and female primordial germ cells in a hermaphrodite, the leech helobdella. [PDF]

open access: yes, 2013
In sexually reproducing animals, primordial germ cells (PGCs) are often set aside early in embryogenesis, a strategy that minimizes the risk of genomic damage associated with replication and mitosis during the cell cycle.
Cho, Sung-Jin   +2 more
core   +2 more sources

Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement

open access: yesPatterns, 2020
Summary: DNA methylation plays an important role in both normal human development and risk of disease. The most utilized method of assessing DNA methylation uses BeadChips, generating an epigenome-wide “snapshot” of >450,000 observations (probe ...
Karen Sugden   +15 more
doaj  

Abnormal methylation mediated upregulation of LINC00857 boosts malignant progression of lung adenocarcinoma by modulating the miR‐486‐5p/NEK2 axis

open access: yesThe Clinical Respiratory Journal, Volume 18, Issue 5, May 2024.
Low methylation of LINC00857 in the promoter region led to its high expression. Knockdown of LINC00857 restrained lymph node metastasis and stimulated radiosensitivity of LUAD cells. LINC00857 acted as a ceRNA, regulating NEK2 expression by binding to miR‐486‐5p.
Haoyu Fu   +4 more
wiley   +1 more source

The 'mechanism' of human cognitive variation [PDF]

open access: yes, 2008
The theory of psychosis and autism as diametrical disorders offers a tractable and testable view of normal and abnormal human cognitive variation as a function of opposing traits grouped by their selection for maternal and paternal reproductive fitness ...
Belmonte, MK
core   +1 more source

The new classes of the genetic algorithms are defined by nonassociative groupoids [PDF]

open access: yesarXiv, 2012
The genetic product of the groupoids, originating in the theory of DNA recombination, is introduced. It permits a natural generalization of the classical genetic algorithm. The full characterization of all three-element genetic groupoids gives an approach to construct the new classes of genetic algorithms.
arxiv  

A Conceptual Approach to Complex Model Management with Generalized Modelling Patterns and Evolutionary Identification

open access: yes, 2018
Complex systems' modeling and simulation are powerful ways to investigate a multitude of natural phenomena providing extended knowledge on their structure and behavior.
Bochenina, Klavdiya O.   +7 more
core   +1 more source

Routes for breaching and protecting genetic privacy [PDF]

open access: yesarXiv, 2013
We are entering the era of ubiquitous genetic information for research, clinical care, and personal curiosity. Sharing these datasets is vital for rapid progress in understanding the genetic basis of human diseases. However, one growing concern is the ability to protect the genetic privacy of the data originators.
arxiv  

Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions [PDF]

open access: yesarXiv, 2011
Genetic interactions have been widely used to define functional relationships between proteins and pathways. In this study, we demonstrated that yeast synthetic lethal genetic interactions can be explained by the genetic interactions between domains of those proteins.
arxiv  

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