Results 1 to 10 of about 33,441 (220)
Epigenetic Modulation of IL-7 and IL-10: Toward Personalized Immune Therapies in Viral Epidemics. [PDF]
J Immunol ResBackground Host immune responses, including cytokine production, shape the severity of viral epidemics. Epigenetic mechanisms such as DNA methylation regulate cytokine gene expression and may contribute to immune dysregulation in severe disease. Methods This study analyzed interleukin‐7 (IL‐7), IL‐8, and IL‐10 promoter methylation in 145 COVID‐19 ...
Yulugkural Z +4 more
europepmc +2 more sources
NeuroprotectionParkinson's disease (PD) is a chronic, progressive neurodegenerative disorder. No disease‐modifying therapies exist. This review proposes that PD susceptibility begins with epigenetic changes and neuroimmune activity—factors that alter gene expression ...
Ayodeji Johnson Ajibare +2 more
doaj +2 more sources
Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development. [PDF]
Mol Reprod DevABSTRACT Germ cells are pivotal for the continuation of biological species. The metazoan germline develops from primordial germ cells (PGCs) that undergo multiple rounds of mitotic divisions. The PGCs are specified by either maternal inheritance of asymmetrically polarized cytoplasmic mRNAs/proteins (found in roundworms, flies, fishes, frogs, and fowl)
Bhattacharya I +5 more
europepmc +2 more sources
Genetic and epigenetic aspects of the and genes in pubertal development and central precocious puberty: A review [PDF]
Precision and Future Medicine, 2023 The onset of puberty is a pivotal developmental milestone, and the release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone is a key factor in the initiation of puberty. Both kisspeptin and its receptor (KISS1) and KISS1 receptor (KISS1R)
Ahreum Kwon
doaj +1 more source
Epigenetic Changes in Asthma: Role of DNA CpG Methylation
Tuberculosis and Respiratory Diseases, 2020 For the past three decades, more than a thousand of genetic studies have been performed to find out the genetic variants responsible for the risk of asthma.
Da-Jeong Bae, Ph.D. +4 more
doaj +3 more sources
The Locus of Affection. Intersubjective Life from Enaction to Epigenesis [PDF]
Phainomena, 2020 How is it possible for me to engage in an intersubjective world? In enactivism, cognition is defined as the living system’s interaction with the meaningful world. What is missing, here, is the conceptualization of intersubjectivity.
Maxim Miroshnichenko
doaj +1 more source
Epigenetic and genetic approach to the transmissibility of dental characteristics in twins: Report of two cases [PDF]
Stomatološki glasnik Srbije, 2011 Transmissibility of dental and jaw characteristics is strongly influenced by environmental factors during the years of extra uterine life when odontogenesis occurs.
Jefferson Martins Ronald +4 more
doaj +1 more source
Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement
Patterns, 2020 Summary: DNA methylation plays an important role in both normal human development and risk of disease. The most utilized method of assessing DNA methylation uses BeadChips, generating an epigenome-wide “snapshot” of >450,000 observations (probe ...
Karen Sugden +15 more
doaj +1 more source
UNIQUE ULTRA-RICH RARE METAL ORES OF THE TOMTOR COMPLEX AND PROBLEM OF THEIR GENESIS [PDF]
Минералогия, 2019 Main genetic models of the formation of ultra-rich rare metal ores of the Tomtor deposit (Yakutia) are compared on the basis of their structural-textural features, mineral composition, and geologic setting: 1) reducing epigenesis of laterite weathering ...
A.V. Lapin, A.V. Tolstov, I.M. Kulikova
doaj +1 more source
[Reprogramming and epigenesis].
Medecine sciences : M/S, 2005 Les succès récents du clonage animal démontrent que le noyau d’une cellule somatique adulte différenciée peut retourner à un état de type embryonnaire, lui permettant de repasser par les étapes qui conduisent à la naissance d’un animal viable et normal.
Beaujean, Nathalie +3 more
openaire +2 more sources