Results 11 to 20 of about 34,722 (203)
NeuroprotectionParkinson's disease (PD) is a chronic, progressive neurodegenerative disorder. No disease‐modifying therapies exist. This review proposes that PD susceptibility begins with epigenetic changes and neuroimmune activity—factors that alter gene expression ...
Ayodeji Johnson Ajibare +2 more
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Bringing Biology Back In: The Unresolved Issue of “Epigenesis” in Kant
Con-textos Kantianos: International Journal of Philosophy, 2015 Epigenesis has become a far more exciting issue in Kant studies recently, especially with the publication of Jennifer Mensch’s Kant’ Organicism. In my commentary, I propose to clarify my own position on epigenesis relative to that of Mensch by once again
John H. Zammito
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Preformation and epigenesis converge to specify primordial germ cell fate in the early Drosophila embryo. [PDF]
PLoS Genetics, 2022 A critical step in animal development is the specification of primordial germ cells (PGCs), the precursors of the germline. Two seemingly mutually exclusive mechanisms are implemented across the animal kingdom: epigenesis and preformation. In epigenesis,
Megan M Colonnetta +5 more
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Genetic and epigenetic aspects of the and genes in pubertal development and central precocious puberty: A review [PDF]
Precision and Future Medicine, 2023 The onset of puberty is a pivotal developmental milestone, and the release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone is a key factor in the initiation of puberty. Both kisspeptin and its receptor (KISS1) and KISS1 receptor (KISS1R)
Ahreum Kwon
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Epigenetic Changes in Asthma: Role of DNA CpG Methylation
Tuberculosis and Respiratory Diseases, 2020 For the past three decades, more than a thousand of genetic studies have been performed to find out the genetic variants responsible for the risk of asthma.
Da-Jeong Bae, Ph.D. +4 more
doaj +3 more sources
The Locus of Affection. Intersubjective Life from Enaction to Epigenesis [PDF]
Phainomena, 2020 How is it possible for me to engage in an intersubjective world? In enactivism, cognition is defined as the living system’s interaction with the meaningful world. What is missing, here, is the conceptualization of intersubjectivity.
Maxim Miroshnichenko
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Chemistry and epigenesis in Diderot and Venel
, 2015 Workshop international Life sciences and philosophy in the late 18th century : epigenesis, form and organization, organisé par I. Goy et P.
Pépin, François
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Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development. [PDF]
Mol Reprod DevABSTRACT Germ cells are pivotal for the continuation of biological species. The metazoan germline develops from primordial germ cells (PGCs) that undergo multiple rounds of mitotic divisions. The PGCs are specified by either maternal inheritance of asymmetrically polarized cytoplasmic mRNAs/proteins (found in roundworms, flies, fishes, frogs, and fowl)
Bhattacharya I +5 more
europepmc +2 more sources
Epigenetic Modulation of IL-7 and IL-10: Toward Personalized Immune Therapies in Viral Epidemics. [PDF]
J Immunol ResBackground Host immune responses, including cytokine production, shape the severity of viral epidemics. Epigenetic mechanisms such as DNA methylation regulate cytokine gene expression and may contribute to immune dysregulation in severe disease. Methods This study analyzed interleukin‐7 (IL‐7), IL‐8, and IL‐10 promoter methylation in 145 COVID‐19 ...
Yulugkural Z +4 more
europepmc +2 more sources
, 2021 Kant’s use of epigenesis differed according to the context within his remarks were made and can be seen to be falling within three main types of consideration. The first of these considered epigenesis as a theory of biological generation.
Mensch, Jennifer
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