Results 81 to 90 of about 43,533 (191)

Expectile Neural Networks for Genetic Data Analysis of Complex Diseases [PDF]

open access: yesarXiv, 2020
The genetic etiologies of common diseases are highly complex and heterogeneous. Classic statistical methods, such as linear regression, have successfully identified numerous genetic variants associated with complex diseases. Nonetheless, for most complex diseases, the identified variants only account for a small proportion of heritability.
arxiv  

Mechanisms For The Environmental Regulation Of Gene Expression: Ecological Aspects Of Animal Development [PDF]

open access: yes, 2005
The environment can play a significant role in the production of phenotypes. However, the developmental mechanisms by which the environmental agents effect normal development are Just becoming known. At least three paths have been found through which the
Gilbert, Scott F.
core   +2 more sources

Scaling laws in critical random Boolean networks with general in- and out-degree distributions

open access: yes, 2013
We evaluate analytically and numerically the size of the frozen core and various scaling laws for critical Boolean networks that have a power-law in- and/or out-degree distribution.
Drossel, Barbara, Möller, Marco
core   +1 more source

Causes that Make a Difference [PDF]

open access: yes, 2007
Biologists studying complex causal systems typically identify some factors as causes and treat other factors as background conditions. For example, when geneticists explain biological phenomena, they often foreground genes and relegate the cellular ...
Waters, C. Kenneth
core   +1 more source

GemTools: A fast and efficient approach to estimating genetic ancestry [PDF]

open access: yesarXiv, 2011
To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computationally efficient tools for modeling genetic ancestry based on SNP genotypes.
arxiv  

What contributes to individual differences in brain structure? [PDF]

open access: yes, 2014
Individual differences in adult human brain structure have been found to reveal a great deal of information about variability in behaviors, cognitive abilities and mental and physical health.
Alexander   +57 more
core   +2 more sources

Misspecification in mixed-model based association analysis [PDF]

open access: yesarXiv, 2015
Additive genetic variance in natural populations is commonly estimated using mixed models, in which the covariance of the genetic effects is modeled by a genetic similarity matrix derived from a dense set of markers. An important but usually implicit assumption is that the presence of any non-additive genetic effect only increases the residual variance,
arxiv  

Schizophrenia, genetics, epigenesis, environment: a systematic review of unifi ed etiological hypotheses and genetic profi le; and a new algorithm to cope with the main fi ndings

open access: yes, 2010
Contexto: la esquizofrenia es un síndrome complejo relacionado con genes y factores de riesgo no genéticos. Estudios epidemiológicos reconocidos reportan su presencia en todas las culturas y regiones geográficas. En este sentido, las Hipótesis Etiológicas Unificadas enfrentan simultáneamente el desafío de presentar los datos experimentales y demostrar ...
Machado Dias, Alvaro   +1 more
openaire   +1 more source

Multiple Representations of Human Genetics in Biology Textbooks [PDF]

open access: yes, 2014
Multiple ways of representing the emerging new genetic knowledge and its implications have resulted from recent research including the Human Genome Project.
Castéra, Jérémy, Clément, Pierre
core   +1 more source

Logic motif of combinatorial control in transcriptional networks [PDF]

open access: yes, 2008
Combinatorial control is prevalent in transcriptional regulatory networks. However, whether there are specific logic patterns over- or under-represented in real networks remains uninvestigated.
Rui Jiang, Xuebing Wu, Zhirong Sun
core   +1 more source

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