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Developmental Science, 2006
AbstractIt is becoming increasingly clear that little in development is predetermined or permanently fixed. Rather, gene expression is activity dependent, and epigenesis is probabilistic. So, the study of genetic disorders needs to change from the still widely held view that developmental disorders can be accounted for in terms of intact versus ...
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AbstractIt is becoming increasingly clear that little in development is predetermined or permanently fixed. Rather, gene expression is activity dependent, and epigenesis is probabilistic. So, the study of genetic disorders needs to change from the still widely held view that developmental disorders can be accounted for in terms of intact versus ...
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The probabilistic epigenesis of knowledge
2006Publisher Summary This chapter outlines an approach that takes knowledge acquisition as an instance of a striking but general, developmental phenomenon, the emergence of new structure. This approach circumvents many of the logical problems of knowledge acquisition and provides a rational framework for integrating seemingly disparate developmental ...
James A. Dixon, Elizabeth Kelley
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Mechanisms of Disease: Epigenesis
Seminars in Pediatric Neurology, 2007Genome-wide epigenetic modification plays a pivotal role in regulating gene expression through chromatin structure and stability, tissue-specific and embryonic developmental specific gene regulation, and genomic imprinting. Mechanisms include chromatin remodeling through histone modification and DNA methylation, RNA associated gene silencing and ...
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MAIN ASPECTS OF THE EPIGENESIS PROBLEM
Sedimentology, 1970SUMMARY This paper presents the main trends in epigenetic research in the U.S.S.R. in the last years: 1 Study of epigenetic zonality in thick series of sedimentary rocks of various ages and tectonic regions, (zones of unaltered clay matrix, of altered clay matrix, of quartzitic structures and hydromica-chloritic cement, and of prick-like ...
A. G. Kossovskaya, V. D. Shutov
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Behavioral and Brain Sciences, 1995
AbstractMealey distinguishes two types of sociopathy: (1) “primary,” or obligate, and (2) “secondary,” or facultative. Either sociopathy evolved twice, or one form is derived from the other, e.g., through: (1) genetic assimilation generating polymorphism in the relative strength of biases favoring the development of otherwise facultative strategies, or
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AbstractMealey distinguishes two types of sociopathy: (1) “primary,” or obligate, and (2) “secondary,” or facultative. Either sociopathy evolved twice, or one form is derived from the other, e.g., through: (1) genetic assimilation generating polymorphism in the relative strength of biases favoring the development of otherwise facultative strategies, or
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Human Development, 2017
What would it mean to take seriously a radically dynamic, life course approach to the epigenesis of obesity? This essay brings together concepts and perspectives from developmental systems theory, evolutionary developmental psychology, critical epidemiology, and public and population health into a complex systems framing of the problem of obesity.
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What would it mean to take seriously a radically dynamic, life course approach to the epigenesis of obesity? This essay brings together concepts and perspectives from developmental systems theory, evolutionary developmental psychology, critical epidemiology, and public and population health into a complex systems framing of the problem of obesity.
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The Epigenesis of an Epigeneticist [PDF]
, 2010 I’m going to begin this essay in the middle of the story, with a question the Johns Hopkins Medical School Admissions Director asked me in the spring of 1971, and also the question David Schwartz asked all of us in creating this book, namely, “Why did you want to become a physician-scientist?” I was a sophomore at Yale, and I had applied to medical ...
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2014
Contents: Preface. Part I: Biological Contributions to Cognition. C.R. Gallistel, A.L. Brown, S. Carey, R. Gelman, F.C. Keil, Lessons From Animal Learning for the Study of Cognitive Development. P. Marler, The Instinct to Learn. A. Diamond, Neuropsychological Insights into the Meaning of Object Concept Development. E.L. Newport, Contrasting Concepts of
Susan Carey, Rochel Gelman
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Contents: Preface. Part I: Biological Contributions to Cognition. C.R. Gallistel, A.L. Brown, S. Carey, R. Gelman, F.C. Keil, Lessons From Animal Learning for the Study of Cognitive Development. P. Marler, The Instinct to Learn. A. Diamond, Neuropsychological Insights into the Meaning of Object Concept Development. E.L. Newport, Contrasting Concepts of
Susan Carey, Rochel Gelman
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Epigenesis: The Missing Beat in Biotechnology?
Nature Biotechnology, 1994The range of human phenotypes/diseases for which our burgeoning bio-molecular data base is sufficient to provide understanding, diagnosis, and therapy is small. Only 2 percent of our total disease load is related to monogenic causality, and even here the final phenotype is modulated by many factors.
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