Results 41 to 50 of about 37,902 (285)

Current status of genome‐wide epigenetic profiling of mammalian preimplantation embryos

open access: yesReproductive Medicine and Biology, Volume 22, Issue 1, January/December 2023., 2023
Abstract Background Genome‐wide information on epigenetic modifications in mammalian preimplantation embryos was an unexplored sanctuary of valuable research insights protected by the difficulty of its analysis. However, that is no longer the case, and many epigenome maps are now available for sightseeing there.
Shuntaro Ikeda
wiley   +1 more source

Gut bacterial profiles in Parkinson's disease: A systematic review

open access: yesCNS Neuroscience &Therapeutics, Volume 29, Issue 1, Page 140-157, January 2023., 2023
The role of gut bacteria in association with Parkinson's disease (PD) may involve the alterations of bacteria with the capacity to produce short‐chain fatty acids (SCFAs) and an increase in putative pathobionts, which may work together to potentially impair the intestinal barrier and/or blood–brain barrier integrity, stimulating systemic and neural ...
Zhe Li   +17 more
wiley   +1 more source

TO THE 250TH ANNIVERSARY OF ANDREI (JĘ Ę DRZEJ) Ę Ś NIADECKI – AN OUTSTANDING BIOLOGIST, CHEMIST, PHYSICIAN, TEACHER AND PUBLIC FIGURE

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
A brief review of the scientific activities of an outstanding biologist, chemist, physician and health care organizer, Professor of the Vilna University, Academician of the St.
Moiseenok A. G.
doaj   +1 more source

KMT2A maintains stemness of gastric cancer cells through regulating Wnt/β-catenin signaling-activated transcriptional factor KLF11

open access: yesOpen Medicine, 2023
The molecular mechanisms of epigenetic regulation in gastric cancer development are not yet well established. In this study, we demonstrated that KMT2A was highly expressed in gastric cancer and associated with poor outcomes of patients and revealed that
Deng Chongwen   +6 more
doaj   +1 more source

Evolution, or Epigenesis? [PDF]

open access: yesNature, 1895
IN the English translation of Prof. Hertwig's book “The Cell,” it is stated (p. 295), “When the female gamete of the Alga Ectocarpus comes to rest, for a few minutes it becomes receptive. If the egg is not fertilised at this time … parthenogenetic germination begins to make its appearance … It may be accepted as a law of nature (italics mine) for ...
openaire   +3 more sources

The modern versus extended evolutionary synthesis : sketch of an intra-genomic gene's eye view for the evolutionary-genetic underpinning of epigenetic and developmental evolution [PDF]

open access: yes, 2018
Studying the phenotypic evolution of organisms in terms of populations of genes and genotypes, the Modern Synthesis (MS) conceptualizes biological evolution in terms of 'inter-organismal' interactions among genes sitting in the different individual ...
Blancke, Stefaan   +2 more
core   +3 more sources

The Number of Different Binary Functions Generated by NK-Kauffman Networks and the Emergence of Genetic Robustness [PDF]

open access: yes, 2007
We determine the average number $ \vartheta (N, K) $, of \textit{NK}-Kauffman networks that give rise to the same binary function. We show that, for $ N \gg 1 $, there exists a connectivity critical value $ K_c $ such that $ \vartheta(N,K) \approx e ...
Bechte W.   +14 more
core   +4 more sources

Promoter DNA Methylation Frequency and Clinicopathological Role of miR-129-2 Gene in Patients with Chronic Lymphocytic Leukemia

open access: yesOman Medical Journal, 2020
Objectives: Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of apparently mature B-type lymphocytes in the lymphohematopoietic organs.
Morteza Hashemi   +3 more
doaj   +1 more source

On the hodological criterion for homology

open access: yesFrontiers in Neuroscience, 2015
Owen’s pre-evolutionary definition of a homologue as the same organ in different animals under every variety of form and function and its redefinition after Darwin as the same trait in different lineages due to common ancestry entail the same heuristic ...
Macarena eFaunes   +4 more
doaj   +1 more source

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